OSU 6162 hydrochloride

Modify Date: 2024-01-11 15:20:17

OSU 6162 hydrochloride structure	Common Name	OSU 6162 hydrochloride
	CAS Number	156907-84-5	Molecular Weight	317.87
	Density	N/A	Boiling Point	436.5ºC at 760 mmHg
	Molecular Formula	C₁₅H₂₄ClNO₂S	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	217.8ºC
	Symbol	GHS07	Signal Word	Warning

Use of OSU 6162 hydrochloride

(-)-OSU6162 (PNU96391) hydrochloride is a dopamine stabilizer. (-)-OSU6162 hydrochloride acts as partial agonist at 5-HT2A and is a dopamine D2 antagonist. (-)-OSU6162 hydrochloride can be used for the research of aggression and irritability[1][2].

Name	(3S)-3-(3-methylsulfonylphenyl)-1-propylpiperidine,hydrochloride
Synonym	More Synonyms

Description	(-)-OSU6162 (PNU96391) hydrochloride is a dopamine stabilizer. (-)-OSU6162 hydrochloride acts as partial agonist at 5-HT2A and is a dopamine D2 antagonist. (-)-OSU6162 hydrochloride can be used for the research of aggression and irritability[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. Carlsson ML, et al. I. In vivo evidence for partial agonist effects of (-)-OSU6162 and (+)-OSU6162 on 5-HT2A serotonin receptors. J Neural Transm (Vienna). 2011 Nov;118(11):1511-22. [2]. Studer E, et al. The effects of the dopamine stabilizer (-)-OSU6162 on aggressive and sexual behavior in rodents. Transl Psychiatry. 2016 Mar 22;6(3):e762.

Description

Related Catalog

Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor

Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

References

[1]. Carlsson ML, et al. I. In vivo evidence for partial agonist effects of (-)-OSU6162 and (+)-OSU6162 on 5-HT2A serotonin receptors. J Neural Transm (Vienna). 2011 Nov;118(11):1511-22.

[2]. Studer E, et al. The effects of the dopamine stabilizer (-)-OSU6162 on aggressive and sexual behavior in rodents. Transl Psychiatry. 2016 Mar 22;6(3):e762.

Boiling Point	436.5ºC at 760 mmHg
Molecular Formula	C₁₅H₂₄ClNO₂S
Molecular Weight	317.87
Flash Point	217.8ºC
Exact Mass	317.12200
PSA	45.76000
LogP	4.50020
Vapour Pressure	8.04E-08mmHg at 25°C

OSU 6162 hydrochloride MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H319
Precautionary Statements	P305 + P351 + P338
RIDADR	NONH for all modes of transport

The dopamine stabilizer (-)-OSU6162 occupies a subpopulation of striatal dopamine D2/D3 receptors: an [(11)C]raclopride PET study in healthy human subjects.

Neuropsychopharmacology 40(2) , 472-9, (2015)

(-)-OSU6162 is a dopamine stabilizer that can counteract both hyperdopaminergic and hypodopaminergic states. In this study, D2/D3 receptor occupancy of (-)-OSU6162 in the human brain was investigated ...

OSU-6162

(S)-(-)-(3-methanesulfonyl-phenyl)-1-propyl-piperidine hydrochloride

OSU6162 hydrochloride

(S,S)-3-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride

OSU 6162 HYDROCHLORIDE

PNU-0096391

OSU-6162 hydrochloride

DC Chemicals Limited
China
Product Name: OSU-6162 hydrochloride
Price: $Inquiry/25mg $Inquiry/100mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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