156907-84-5

156907-84-5 structure

Name: OSU 6162 hydrochloride
Chemical Name: (3S)-3-(3-methylsulfonylphenyl)-1-propylpiperidine,hydrochloride
CAS Number: 156907-84-5
Molecular Formula: C₁₅H₂₄ClNO₂S
Molecular Weight: 317.87
Catalog: Signaling Pathways GPCR/G Protein 5-HT Receptor
Create Date: 2017-01-12 17:51:14
Modify Date: 2025-08-24 22:39:19
(-)-OSU6162 (PNU96391) hydrochloride is a dopamine stabilizer. (-)-OSU6162 hydrochloride acts as partial agonist at 5-HT2A and is a dopamine D2 antagonist. (-)-OSU6162 hydrochloride can be used for the research of aggression and irritability[1][2].

Name	(3S)-3-(3-methylsulfonylphenyl)-1-propylpiperidine,hydrochloride
Synonyms	OSU-6162 (S)-(-)-(3-methanesulfonyl-phenyl)-1-propyl-piperidine hydrochloride OSU6162 hydrochloride (S,S)-3-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride OSU 6162 HYDROCHLORIDE PNU-0096391 OSU-6162 hydrochloride

Description	(-)-OSU6162 (PNU96391) hydrochloride is a dopamine stabilizer. (-)-OSU6162 hydrochloride acts as partial agonist at 5-HT2A and is a dopamine D2 antagonist. (-)-OSU6162 hydrochloride can be used for the research of aggression and irritability[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
References	[1]. Carlsson ML, et al. I. In vivo evidence for partial agonist effects of (-)-OSU6162 and (+)-OSU6162 on 5-HT2A serotonin receptors. J Neural Transm (Vienna). 2011 Nov;118(11):1511-22. [2]. Studer E, et al. The effects of the dopamine stabilizer (-)-OSU6162 on aggressive and sexual behavior in rodents. Transl Psychiatry. 2016 Mar 22;6(3):e762.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H319
Precautionary Statements	P305 + P351 + P338
RIDADR	NONH for all modes of transport