AF 102A hydrochloride

Modify Date: 2025-08-25 18:41:02

AF 102A hydrochloride Structure
AF 102A hydrochloride structure
 Common Name AF 102A hydrochloride
CAS Number 107220-29-1 Molecular Weight 235.77400
Density N/A Boiling Point 308.5ºC at 760mmHg
Molecular Formula C10H18ClNOS Melting Point N/A
MSDS N/A Flash Point 140.4ºC

 Use of AF 102A hydrochloride


Trans-Cevimeline (AF102A) (hydrochloride), as a trans-isomer of AF102B, is a M1 selective cholinergic agonist. Trans-Cevimeline (AF102A) (hydrochloride) can be used for the research of Alzheimer's disease[1].

 Names

Name (2R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane],hydrochloride
Synonym More Synonyms

 AF 102A hydrochloride Biological Activity

Description Trans-Cevimeline (AF102A) (hydrochloride), as a trans-isomer of AF102B, is a M1 selective cholinergic agonist. Trans-Cevimeline (AF102A) (hydrochloride) can be used for the research of Alzheimer's disease[1].
Related Catalog
Target

M1[1]

In Vivo AF102A (1 mg/kg; i.p.) reverses cognitive impairments in a step-through passive avoidance task[1]. Animal Model: Rats[1] Dosage: 1 mg/kg Administration: I.p. Result: Reversed cognitive impairments in a step-through passive avoidance task.
References

[1]. Fisher A, et al. (+-)-cis-2-methyl-spiro(1,3-oxathiolane-5,3')quinuclidine, an M1 selective cholinergic agonist, attenuates cognitive dysfunctions in an animal model of Alzheimer's disease. J Pharmacol Exp Ther. 1991;257(1):392-403.

 Chemical & Physical Properties

Boiling Point 308.5ºC at 760mmHg
Molecular Formula C10H18ClNOS
Molecular Weight 235.77400
Flash Point 140.4ºC
Exact Mass 235.08000
PSA 37.77000
LogP 2.30010
Vapour Pressure 0.000676mmHg at 25°C

 Synonyms

AF 102A HCl
trans-Cevimeline Hydrochloride
AF 102A hydrochloride
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

AF 102A hydrochloride suppliers

AF 102A hydrochloride price

Related Compounds: More...
Alectinib hydrochloride
1256589-74-8
2-[2-chloroethyl(ethyl)amino]ethyl acetate,hydrochloride
103994-00-9
(3-alpha,16-alpha)-Eburnamenin-14-carboxylsaeure-phthalidylester hydro chlorid [German]
82958-12-1
3-phenyl-5-(3-piperidin-1-ylpropyl)-1,2,4-oxadiazole,hydrochloride
97739-32-7
Dapiprazole Hydrochloride
72822-13-0
2,2-Difluorocyclopropanamine hydrochloride
105614-25-3
af-353 Hydrochloride
927887-18-1
Cevimeline hydrochloride
107220-28-0
(diethyl)[3-phenyl-1,2,4-oxadiazole-5-ethyl]ammonium chloride
1219-20-1
6-chloro-4-oxo-N-[3-(trifluoromethyl)phenyl]-4H-chromene-2-carboxamide
880400-16-8
4-(benzenesulfonyl)-5-(3-butoxyphenyl)-3-hydroxy-1-(4-methylphenyl)-2,5-dihydro-1H-pyrrol-2-one
880400-57-7
N-(furan-2-ylmethyl)-N-(4-methylbenzyl)-2-(4-methylphenoxy)acetamide
880401-51-4
N-(3-chloro-2-methylphenyl)-2-(5-methyl-1-benzofuran-3-yl)acetamide
881217-38-5
N-(3-chloro-4-methylphenyl)-2-(5-methyl-1-benzofuran-3-yl)acetamide
880401-61-6
N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(4-fluorobenzyl)-2-(5-methyl-1-benzofuran-3-yl)acetamide
880401-81-0
N-(1,1-dioxidotetrahydrothiophen-3-yl)-2-[5-(propan-2-yl)-1-benzofuran-3-yl]-N-[4-(propan-2-yl)benzyl]acetamide
880401-86-5
N-(1,1-dioxidotetrahydrothiophen-3-yl)-2-(5-methyl-1-benzofuran-3-yl)-N-(4-methylbenzyl)acetamide
880401-91-2
N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-(4-methylbenzyl)-2-[5-(propan-2-yl)-1-benzofuran-3-yl]acetamide
880401-96-7
N-(4-chlorobenzyl)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-2-[5-(propan-2-yl)-1-benzofuran-3-yl]acetamide
880402-01-7
Chemsrc provides AF 102A hydrochloride(CAS#:107220-29-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of AF 102A hydrochloride are included as well.>> amp version: AF 102A hydrochloride

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved