(E)-1,2-Dichloroethene

Modify Date: 2024-01-02 10:27:56

(E)-1,2-Dichloroethene Structure
(E)-1,2-Dichloroethene structure
Common Name (E)-1,2-Dichloroethene
CAS Number 156-60-5 Molecular Weight 96.943
Density 1.2±0.1 g/cm3 Boiling Point 47.7±0.0 °C at 760 mmHg
Molecular Formula C2H2Cl2 Melting Point -57ºC(lit.)
MSDS Chinese USA Flash Point 6.1±0.0 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Names

Name trans-1,2-dichloroethene
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 47.7±0.0 °C at 760 mmHg
Melting Point -57ºC(lit.)
Molecular Formula C2H2Cl2
Molecular Weight 96.943
Flash Point 6.1±0.0 °C
Exact Mass 95.953354
LogP 1.75
Vapour Pressure 333.1±0.0 mmHg at 25°C
Index of Refraction 1.453
Stability Incompatible with oxidizing agents, bases. Stable, but may decompose on exposure to air, moisture or light. Highly flammable.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KV9400000
CHEMICAL NAME :
Ethylene, 1,2-dichloro-, (E)-
CAS REGISTRY NUMBER :
156-60-5
BEILSTEIN REFERENCE NO. :
1420761
LAST UPDATED :
199803
DATA ITEMS CITED :
24
MOLECULAR FORMULA :
C2-H2-Cl2
MOLECULAR WEIGHT :
96.94
WISWESSER LINE NOTATION :
G1U1G -T

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Human
DOSE/DURATION :
4800 mg/m3/10M
TOXIC EFFECTS :
Behavioral - sleep Behavioral - hallucinations, distorted perceptions
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1235 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7411 mg/kg
TOXIC EFFECTS :
Cardiac - other changes Lungs, Thorax, or Respiration - other changes Liver - fatty liver degeneration
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2122 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - ataxia
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
75 gm/m3/2H
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3952 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
43 gm/m3/6H
TOXIC EFFECTS :
Behavioral - general anesthetic Behavioral - convulsions or effect on seizure threshold Gastrointestinal - nausea or vomiting
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Skin and Appendages - dermatitis, irritative (after systemic exposure) Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
113 gm/kg/90D-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in bladder weight
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 ppm/8H/16W-I
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes Liver - other changes Endocrine - changes in endocrine weight (unspecified)
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
DOSE :
6000 ppm/6H
SEX/DURATION :
female 7-16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
DOSE :
12000 ppm/6H
SEX/DURATION :
female 7-16 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :
Sex chromosome loss and nondisjunction
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
6500 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 182,135,1987

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H225-H332-H412
Precautionary Statements P210-P273
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)
Hazard Codes Xn: Harmful;F: Flammable;T: Toxic;
Risk Phrases R11;R20;R52/53
Safety Phrases 7-16-29-61-45-36/37
RIDADR UN 1150 3/PG 2
WGK Germany 2
RTECS KV9400000
Packaging Group II
Hazard Class 3
HS Code 2903299090

 Synthetic Route

 Customs

HS Code 2903299090
Summary 2903299090 other unsaturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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 Synonyms

Acetylene dichloride, trans-
E-1,2-dichloroethene
trans-1, 2-Dichloroethene
trans-1,2-Dichloroethylene,stabilized
1,2-Dichloroethene, trans-
(E)-1,2-dichloroethylene
Ethylene, 1,2-dichloro-, (E)-
trans-dichloroethylene
Dichloroethylene, trans-
Ethene, 1,2-dichloro-, (1E)-
1,2-Dichloroethylene (trans)
Ethene, 1,2-dichloro-, (E)- (9CI)
TRANS-ACETYLENE DICHLORIDE
1,2-trans-dichloroethene
trans-1,2-DCE
Ethene, 1,2-dichloro-, (E)-
Ethylene, 1,2-dichloro-, trans-
1,2-trans-dichloroethylene
TRANS-1,2-DICHLOROETHENE
acetylene dichloride
trans-1,2-Dichloroethylene
ethene, (E)-1,2-dichloro-
EINECS 205-860-2
1,2-dichloroethylene
MFCD00062942