(E)-1,2-Dichloroethene

Names

[ CAS No. ]:
156-60-5

[ Name ]:
(E)-1,2-Dichloroethene

[Synonym ]:
Acetylene dichloride, trans-
E-1,2-dichloroethene
trans-1, 2-Dichloroethene
trans-1,2-Dichloroethylene,stabilized
1,2-Dichloroethene, trans-
(E)-1,2-dichloroethylene
Ethylene, 1,2-dichloro-, (E)-
trans-dichloroethylene
Dichloroethylene, trans-
Ethene, 1,2-dichloro-, (1E)-
1,2-Dichloroethylene (trans)
Ethene, 1,2-dichloro-, (E)- (9CI)
TRANS-ACETYLENE DICHLORIDE
1,2-trans-dichloroethene
trans-1,2-DCE
Ethene, 1,2-dichloro-, (E)-
Ethylene, 1,2-dichloro-, trans-
1,2-trans-dichloroethylene
TRANS-1,2-DICHLOROETHENE
acetylene dichloride
trans-1,2-Dichloroethylene
ethene, (E)-1,2-dichloro-
EINECS 205-860-2
1,2-dichloroethylene
MFCD00062942

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
47.7±0.0 °C at 760 mmHg

[ Melting Point ]:
-57ºC(lit.)

[ Molecular Formula ]:
C₂H₂Cl₂

[ Molecular Weight ]:
96.943

[ Flash Point ]:
6.1±0.0 °C

[ Exact Mass ]:
95.953354

[ LogP ]:
1.75

[ Vapour Pressure ]:
333.1±0.0 mmHg at 25°C

[ Index of Refraction ]:
1.453

[ Stability ]:
Incompatible with oxidizing agents, bases. Stable, but may decompose on exposure to air, moisture or light. Highly flammable.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KV9400000

CHEMICAL NAME :: Ethylene, 1,2-dichloro-, (E)-

CAS REGISTRY NUMBER :: 156-60-5

BEILSTEIN REFERENCE NO. :: 1420761

LAST UPDATED :: 199803

DATA ITEMS CITED :: 24

MOLECULAR FORMULA :: C2-H2-Cl2

MOLECULAR WEIGHT :: 96.94

WISWESSER LINE NOTATION :: G1U1G -T

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Human

DOSE/DURATION :: 4800 mg/m3/10M

TOXIC EFFECTS :: Behavioral - sleep Behavioral - hallucinations, distorted perceptions

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1235 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7411 mg/kg

TOXIC EFFECTS :: Cardiac - other changes Lungs, Thorax, or Respiration - other changes Liver - fatty liver degeneration

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2122 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - ataxia

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 75 gm/m3/2H

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3952 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 43 gm/m3/6H

TOXIC EFFECTS :: Behavioral - general anesthetic Behavioral - convulsions or effect on seizure threshold Gastrointestinal - nausea or vomiting

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Skin and Appendages - dermatitis, irritative (after systemic exposure) Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 113 gm/kg/90D-C

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in bladder weight

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 ppm/8H/16W-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Liver - other changes Endocrine - changes in endocrine weight (unspecified)

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 6000 ppm/6H

SEX/DURATION :: female 7-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 12000 ppm/6H

SEX/DURATION :: female 7-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

MUTATION DATA

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 6500 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 182,135,1987

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H332-H412

[ Precautionary Statements ]:
P210-P273

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xn: Harmful;F: Flammable;T: Toxic;

[ Risk Phrases ]:
R11;R20;R52/53

[ Safety Phrases ]:
7-16-29-61-45-36/37

[ RIDADR ]:
UN 1150 3/PG 2

[ WGK Germany ]:
2

[ RTECS ]:
KV9400000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
2903299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2903299090

[ Summary ]:
2903299090 other unsaturated chlorinated derivatives of acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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