PF-06455943
Modify Date: 2025-08-22 12:23:27
PF-06455943 structure
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Common Name | PF-06455943 | ||
|---|---|---|---|---|
| CAS Number | 1527474-15-2 | Molecular Weight | 323.32 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H14FN5O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PF-06455943PF-06455943 is a leucine rich repeat kinase 2 (LRRK2) inhibitor with IC50 value of 3 nM. PF-06455943 also is a PET radioligand. PF-06455943 can be used for the research of ADME/neuro PK characterization and Parkinson disease (PD)[1][2]. |
| Name | PF-06455943 |
|---|
| Description | PF-06455943 is a leucine rich repeat kinase 2 (LRRK2) inhibitor with IC50 value of 3 nM. PF-06455943 also is a PET radioligand. PF-06455943 can be used for the research of ADME/neuro PK characterization and Parkinson disease (PD)[1][2]. |
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| Related Catalog | |
| In Vitro | PF-06455943 (Compound 22) has inhibition activity for LRRK2 with IC50 values of 3 nM (WT), 9 nM (G2019S) and 20 nM (cellular WCA), respectively[1]. |
| Molecular Formula | C17H14FN5O |
|---|---|
| Molecular Weight | 323.32 |