PF-06455943
Names
[ CAS No. ]:
1527474-15-2
[ Name ]:
PF-06455943
Biological Activity
[Description]:
PF-06455943 is a leucine rich repeat kinase 2 (LRRK2) inhibitor with IC50 value of 3 nM. PF-06455943 also is a PET radioligand. PF-06455943 can be used for the research of ADME/neuro PK characterization and Parkinson disease (PD)[1][2].
[Related Catalog]:
[In Vitro]
PF-06455943 (Compound 22) has inhibition activity for LRRK2 with IC50 values of 3 nM (WT), 9 nM (G2019S) and 20 nM (cellular WCA), respectively[1].
Chemical & Physical Properties
[ Molecular Formula ]:
C17H14FN5O
[ Molecular Weight ]:
323.32