UCM 608

Modify Date: 2024-01-02 14:51:45

UCM 608 Structure
UCM 608 structure
Common Name UCM 608
CAS Number 151889-03-1 Molecular Weight 308.37
Density 1.172g/cm3 Boiling Point 612.4ºC at 760 mmHg
Molecular Formula C19H20N2O2 Melting Point N/A
MSDS N/A Flash Point 324.2ºC

 Use of UCM 608


UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4[1][2].

 Names

Name N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide
Synonym More Synonyms

 UCM 608 Biological Activity

Description UCM 608 is a high affinity melatonin (MT) membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4[1][2].
Related Catalog
Target

pKi: 10.7 (MT1)[1]. pKi: 10.4 (MT2)[1]

In Vitro UCM 608 is a high affinity melatonin membrane receptor agonist. The pKi values for MT1 and MT2 are 10.7 and 10.4 [1].
References

[1]. Radogna F, et al. Rapid and transient stimulation of intracellular reactive oxygen species by melatonin in normal and tumor leukocytes. Toxicol Appl Pharmacol. 2009;239(1):37-45.

[2]. Mor, M., et al. Synthesis, pharmacological characterization and QSAR studies on 2-substituted indole melatonin receptor ligands. Bioorganic & Medicinal Chemistry, 9(4), 1045–1057.

 Chemical & Physical Properties

Density 1.172g/cm3
Boiling Point 612.4ºC at 760 mmHg
Molecular Formula C19H20N2O2
Molecular Weight 308.37
Flash Point 324.2ºC
Exact Mass 308.15200
PSA 54.12000
LogP 3.91300
Vapour Pressure 6.16E-15mmHg at 25°C
Index of Refraction 1.619

 Synonyms

Carcinine ditrifluoroacetate
2-PHENYLMELATONIN
Tocris-0680
HMS3266J05
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