CID-46943215

Modify Date: 2024-02-28 18:36:27

CID-46943215 Structure
CID-46943215 structure
Common Name CID-46943215
CAS Number 1462267-08-8 Molecular Weight 496.35
Density 1.4±0.1 g/cm3 Boiling Point 724.2±60.0 °C at 760 mmHg
Molecular Formula C24H22BrN3O4 Melting Point N/A
MSDS N/A Flash Point 391.8±32.9 °C

 Use of CID-46943215


ML266 is glucocerebrosidase (GCase) molecule chaperone with IC50 of 2.5 µM. ML266 binds to GCase and transports of the mutant protein to the lysosome, and resume the activity of GCase. ML266 dose not inhibit the GCase enzyme’s action. ML266 has the potential for the research of gaucher disease[1].

 Names

Name 2-{2-[(4-Bromophenyl)amino]-2-oxoethoxy}-N-{2-[methyl(phenyl)amino]-2-oxoethyl}benzamide
Synonym More Synonyms

 CID-46943215 Biological Activity

Description ML266 is glucocerebrosidase (GCase) molecule chaperone with IC50 of 2.5 µM. ML266 binds to GCase and transports of the mutant protein to the lysosome, and resume the activity of GCase. ML266 dose not inhibit the GCase enzyme’s action. ML266 has the potential for the research of gaucher disease[1].
Related Catalog
References

[1]. Rogers S, et al. Discovery, SAR, and Biological Evaluation of Non-inhibitory Chaperones of Glucocerebrosidase. 2012 Mar 27 [updated 2013 Mar 7].

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 724.2±60.0 °C at 760 mmHg
Molecular Formula C24H22BrN3O4
Molecular Weight 496.35
Flash Point 391.8±32.9 °C
Exact Mass 495.079376
LogP 3.47
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.659

 Synonyms

Benzamide, 2-[2-[(4-bromophenyl)amino]-2-oxoethoxy]-N-[2-(methylphenylamino)-2-oxoethyl]-
2-{2-[(4-Bromophenyl)amino]-2-oxoethoxy}-N-{2-[methyl(phenyl)amino]-2-oxoethyl}benzamide
CID-46943215
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