Top Suppliers:I want be here
Related CAS#:
638156-11-3 834903-43-4
15341-31-8 852935-07-0
264233-05-8 749872-43-3
314042-01-8 313493-80-0
370586-05-3 2060006-09-7
946484-84-0 1027951-36-5
94390-15-5 946837-97-4
934461-61-7 1099665-56-1
908499-54-7 908507-01-7
165280-21-7 908507-29-9

638156-11-3

638156-11-3 structure
638156-11-3 structure
  • Name: CID-2011756
  • Chemical Name: 5-(3-chlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide
  • CAS Number: 638156-11-3
  • Molecular Formula: C22H21ClN2O3
  • Molecular Weight: 396.867
  • Catalog: Signaling Pathways Apoptosis PKD
  • Create Date: 2018-12-20 17:40:33
  • Modify Date: 2025-08-21 08:58:08
  • CID 2011756 is an ATP competitive PKD inhibitor, with an IC50 of 3.2 µM for PKD1 in cell free assay, and also shows cellular pan-PKD inhibitory activity against PKD2 and PKD3 (IC50, 0.6 and 0.7 µM, respectively). CID 2011756 also has antitumor activity.
Name 5-(3-chlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide
Synonyms QCR-12
5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furamide
HMS2426M13
2-Furancarboxamide, 5-(3-chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-
cc-693
CID-2011756
CID 2011756
Description CID 2011756 is an ATP competitive PKD inhibitor, with an IC50 of 3.2 µM for PKD1 in cell free assay, and also shows cellular pan-PKD inhibitory activity against PKD2 and PKD3 (IC50, 0.6 and 0.7 µM, respectively). CID 2011756 also has antitumor activity.
Related Catalog
Target

Cellular PKD2:0.6 μM (IC50)

Cellular PKD3:0.7 μM (IC50)

PKD1:3.2 μM (IC50)

In Vitro CID 2011756 is an ATP-competitive PKD1 inhibitor, with an IC50 of 3.2 µM. CID 2011756 decreases the phosphorylation of endogenous PKD1 Ser916 in LNCaP cancer cells with an EC50 of 10±0.7 µM. CID 2011756 also has cellular pan-PKD inhibitory effects, with IC50s of 0.6±0.1 µM and 0.7±0.2 µM for PKD2 and PKD3, respectively[1].
References

[1]. Sharlow ER, et al. Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity. PLoS One. 2011;6(10):e25134.
Density 1.3±0.1 g/cm3
Boiling Point 491.0±45.0 °C at 760 mmHg
Molecular Formula C22H21ClN2O3
Molecular Weight 396.867
Flash Point 250.8±28.7 °C
Exact Mass 396.124084
PSA 58.20000
LogP 3.69
Appearance white solid
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.633
Storage condition -20℃
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H319
Precautionary Statements P305 + P351 + P338
RIDADR NONH for all modes of transport
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Chemsrc provides CAS#:638156-11-3 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 638156-11-3 | Chemsrc address: https://www.chemsrc.com/en/baike/454844.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved