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1462267-08-8

1462267-08-8 structure
1462267-08-8 structure
  • Name: CID-46943215
  • Chemical Name: 2-{2-[(4-Bromophenyl)amino]-2-oxoethoxy}-N-{2-[methyl(phenyl)amino]-2-oxoethyl}benzamide
  • CAS Number: 1462267-08-8
  • Molecular Formula: C24H22BrN3O4
  • Molecular Weight: 496.35
  • Catalog: Research Areas Others
  • Create Date: 2018-06-14 02:15:21
  • Modify Date: 2024-02-28 18:36:27
  • ML266 is glucocerebrosidase (GCase) molecule chaperone with IC50 of 2.5 µM. ML266 binds to GCase and transports of the mutant protein to the lysosome, and resume the activity of GCase. ML266 dose not inhibit the GCase enzyme’s action. ML266 has the potential for the research of gaucher disease[1].

Name 2-{2-[(4-Bromophenyl)amino]-2-oxoethoxy}-N-{2-[methyl(phenyl)amino]-2-oxoethyl}benzamide
Synonyms Benzamide, 2-[2-[(4-bromophenyl)amino]-2-oxoethoxy]-N-[2-(methylphenylamino)-2-oxoethyl]-
2-{2-[(4-Bromophenyl)amino]-2-oxoethoxy}-N-{2-[methyl(phenyl)amino]-2-oxoethyl}benzamide
CID-46943215
Description ML266 is glucocerebrosidase (GCase) molecule chaperone with IC50 of 2.5 µM. ML266 binds to GCase and transports of the mutant protein to the lysosome, and resume the activity of GCase. ML266 dose not inhibit the GCase enzyme’s action. ML266 has the potential for the research of gaucher disease[1].
Related Catalog
References

[1]. Rogers S, et al. Discovery, SAR, and Biological Evaluation of Non-inhibitory Chaperones of Glucocerebrosidase. 2012 Mar 27 [updated 2013 Mar 7].

Density 1.4±0.1 g/cm3
Boiling Point 724.2±60.0 °C at 760 mmHg
Molecular Formula C24H22BrN3O4
Molecular Weight 496.35
Flash Point 391.8±32.9 °C
Exact Mass 495.079376
LogP 3.47
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.659