TBHBA

Modify Date: 2025-08-22 17:58:54

TBHBA Structure
TBHBA structure
Common Name TBHBA
CAS Number 14348-40-4 Molecular Weight 374.809
Density 2.5±0.1 g/cm3 Boiling Point 355.3±42.0 °C at 760 mmHg
Molecular Formula C7H3Br3O3 Melting Point 145-148 °C(lit.)
MSDS Chinese USA Flash Point 168.7±27.9 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of TBHBA


The Boehringer Mannheim cholesterol esterase/cholesterol oxidase/peroxidase/3,4-dichlorophenol kinetic reagent was modified by the inclusion of 2,4,6-tribromo-3-hydroxybenzoic acid which reacts with hydrogen peroxide and 4-aminophenazone to produce a quinone-imine dye with a greater molar absorptivity than that produced with phenol.

 Names

Name 3-Hydroxy-2,4,6-tribromobenzoic acid
Synonym More Synonyms

 TBHBA Biological Activity

Description The Boehringer Mannheim cholesterol esterase/cholesterol oxidase/peroxidase/3,4-dichlorophenol kinetic reagent was modified by the inclusion of 2,4,6-tribromo-3-hydroxybenzoic acid which reacts with hydrogen peroxide and 4-aminophenazone to produce a quinone-imine dye with a greater molar absorptivity than that produced with phenol.
Related Catalog
References

[1]. Moshides JS. Kinetic enzymatic method for automated determination of HDL cholesterol in plasma. J Clin Chem Clin Biochem. 1987 Sep;25(9):583-7.

 Chemical & Physical Properties

Density 2.5±0.1 g/cm3
Boiling Point 355.3±42.0 °C at 760 mmHg
Melting Point 145-148 °C(lit.)
Molecular Formula C7H3Br3O3
Molecular Weight 374.809
Flash Point 168.7±27.9 °C
Exact Mass 371.763214
PSA 57.53000
LogP 3.50
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.709
Storage condition Store at RT.
Water Solubility insoluble

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H312-H315-H319-H332-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R20/22;R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2918290000

 Synthetic Route

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TBHBA Structure

TBHBA

CAS#:14348-40-4

Literature: Bulletin de la Societe Chimique de France, , vol. <2> 46, p. 278

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TBHBA Structure

TBHBA

CAS#:14348-40-4

Literature: Journal of the Chemical Society, , vol. 81, p. 1480 Gazzetta Chimica Italiana, , vol. 32 II, p. 337

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TBHBA Structure

TBHBA

CAS#:14348-40-4

Literature: Journal of the American Chemical Society, , vol. 46, p. 2500

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TBHBA Structure

TBHBA

CAS#:14348-40-4

Detail
Literature: Gazzetta Chimica Italiana, , vol. 32 II, p. 337 Recueil des Travaux Chimiques des Pays-Bas, , vol. 40, p. 628 Monatshefte fuer Chemie, , vol. 34, p. 381 Monatshefte fuer Chemie, , vol. 35, p. 3

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TBHBA Structure

TBHBA

CAS#:14348-40-4

Literature: Bulletin de la Societe Chimique de France, , vol. <4> 41, p. 1363

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TBHBA Structure

TBHBA

CAS#:14348-40-4

Literature: Journal of the Chemical Society, , vol. 81, p. 1480

 Customs

HS Code 2918290000
Summary HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

 Articles7

More Articles
An enzymic assay for uric acid in serum and urine compared with HPLC.

J. Clin. Chem. Clin. Biochem. 27(3) , 151-6, (1989)

We evaluated a colorimetric method for the assay of uric acid in serum or urine, which utilises a Trinder chromogenic system modified by the inclusion of 2,4,6-tribromo-3-hydroxybenzoic acid for oxida...

Determination of HDL-cholesterol using 2,4,6-tribromo-3-hydroxybenzoic acid with a commercial CHOD-PAP reagent.

Ann. Clin. Biochem. 21 ( Pt 5) , 430-3, (1984)

The Boehringer one-component high-performance cholesterol oxidase reagent has been modified by the inclusion of 2,4,6-tribromo-3-hydroxybenzoic acid (TBHBA) to give a fourfold increase in sensitivity ...

Enzymic determination of the free cholesterol fraction of high-density lipoprotein in plasma with use of 2,4,6-tribromo-3-hydroxybenzoic acid.

Clin. Chem. 34(9) , 1799-804, (1988)

A highly sensitive enzymic colorimetric reagent is described for determination of the free cholesterol fraction of high-density lipoprotein (HDL), which represents about 20% of the total cholesterol c...

 Synonyms

Benzoic acid, 2,4,6-tribromo-3-hydroxy-
2,4,6-Tribromo-3-hydroxybenzoic acid (TBHBA)
2,4,6-Tribromo-3-hydroxybenzoic acid
MFCD00055557
TBHBA
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