LY 2955303 structure
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Common Name | LY 2955303 | ||
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CAS Number | 1433497-19-8 | Molecular Weight | 578.74 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C36H42N4O3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of LY 2955303LY2955303 is a potent and selective retinoic acid receptor gamma (RARγ) antagonist with a Ki of 1.09 nM. |
Name | LY2955303 |
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Description | LY2955303 is a potent and selective retinoic acid receptor gamma (RARγ) antagonist with a Ki of 1.09 nM. |
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Related Catalog | |
Target |
Ki: 1.09 nM (RARγ)[1] |
In Vitro | LY2955303 is tested and observed that the binding Kis for RARα, RARβ and RARγ are >1700, >2980 and 1.09 nM, respectively. The functional Ki for RARγ is 7.1±4.9 nM[1]. |
In Vivo | A single oral dose of LY2955303 demonstrates a dose responsive effect whereby the rat reduces differential weight bearing (ED50=0.72 mg/kg)[1]. |
References |
Molecular Formula | C36H42N4O3 |
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Molecular Weight | 578.74 |
Storage condition | 2-8℃ |
Hazard Codes | Xn |
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