LY 295427
Modify Date: 2025-09-06 11:06:59
LY 295427 structure
|
Common Name | LY 295427 | ||
|---|---|---|---|---|
| CAS Number | 152755-31-2 | Molecular Weight | 428.73300 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H52O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LY 295427LY 295427 is a LDL receptor modulator and a hypocholesterolemic agent. LY 295427 derepresses the transcription of the LDLR (LDL Receptor). LY 295427 can be used for hypercholesterolemia research[1][2][3]. |
| Name | ly295427 |
|---|---|
| Synonym | More Synonyms |
| Description | LY 295427 is a LDL receptor modulator and a hypocholesterolemic agent. LY 295427 derepresses the transcription of the LDLR (LDL Receptor). LY 295427 can be used for hypercholesterolemia research[1][2][3]. |
|---|---|
| Related Catalog | |
| In Vitro | LY 295427 时间依赖性地增加中国仓鼠卵巢 (CHO) 细胞对 25-OH chol 的摄取[1]。 LY 295427 (2.9 μM) 提高 30% LDL 受体启动子的活性[2]。 |
| In Vivo | LY 295427 剂量依赖性地降低胆固醇-椰子油喂养的仓鼠 LDL-R 转录水平，ED50 值为 40 mg/kg/day[3]。 |
| References |
| Molecular Formula | C30H52O |
|---|---|
| Molecular Weight | 428.73300 |
| Exact Mass | 428.40200 |
| PSA | 20.23000 |
| LogP | 8.27080 |
| InChIKey | GSFDFZOSYZNZOA-ROMNCUSUSA-N |
| SMILES | C=CCC1C(O)CCC2(C)C1CCC1C3CCC(C(C)CCCC(C)C)C3(C)CCC12 |
| [4α,5α]-4-(2-propenyl)cholestan-3α-ol |
| (3α,4α,5α)-4-(2-propenyl)cholestan-3-ol |
| (3R,4S,5S,8S,9S,10R,13R,14S,17R)-4-Allyl-17-((R)-1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-ol |