Netarsudil mesylate

Modify Date: 2024-01-02 18:29:38

Netarsudil mesylate structure	Common Name	Netarsudil mesylate
	CAS Number	1422144-42-0	Molecular Weight	645.744
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₀H₃₅N₃O₉S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Netarsudil mesylate

Netarsudil mesylate is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes.

Name	Netarsudil mesylate
Synonym	More Synonyms

Description	Netarsudil mesylate is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes.
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> ROCK Signaling Pathways >> Stem Cell/Wnt >> ROCK Signaling Pathways >> TGF-beta/Smad >> ROCK Research Areas >> Others
References	[1]. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4. [2]. Levy B, et al. Ocular hypotensive safety and systemic absorption of AR-13324 ophthalmic solution in normal volunteers. Am J Ophthalmol. 2015 May;159(5):980-5.e1.

Description

Netarsudil mesylate is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes.

Related Catalog

Signaling Pathways >> Cell Cycle/DNA Damage >> ROCK

Signaling Pathways >> Stem Cell/Wnt >> ROCK

Signaling Pathways >> TGF-beta/Smad >> ROCK

Research Areas >> Others

References

[1]. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4.

[2]. Levy B, et al. Ocular hypotensive safety and systemic absorption of AR-13324 ophthalmic solution in normal volunteers. Am J Ophthalmol. 2015 May;159(5):980-5.e1.

Molecular Formula	C₃₀H₃₅N₃O₉S₂
Molecular Weight	645.744
Exact Mass	645.181458
Storage condition	2-8℃

Netarsudil mesylate

4-[(2S)-3-Amino-1-(6-isoquinolinylamino)-1-oxo-2-propanyl]benzyl 2,4-dimethylbenzoate methanesulfonate (1:2)

Methansulfonsäure --4-[(2S)-3-amino-1-(6-isochinolinylamino)-1-oxo-2-propanyl]benzyl-2,4-dimethylbenzoat (2:1)

Acide méthanesulfonique - 2,4-diméthylbenzoate de 4-[(2S)-3-amino-1-(6-isoquinoléinylamino)-1-oxo-2-propanyl]benzyle (2:1)

Benzoic acid, 2,4-dimethyl-, [4-[(1S)-1-(aminomethyl)-2-(6-isoquinolinylamino)-2-oxoethyl]phenyl]methyl ester, methanesulfonate (1:2)

AR-13324 (mesylate)

Henan Tianfu Chemical Co., Ltd.
China
Product Name: AR-13324 (mesylate)
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Price: ￥3978/10 mM * 1 mL in DMSO

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Netarsudil mesylate

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