202464-88-8

202464-88-8 structure

Name: TVP1022 (mesylate)
Chemical Name: S-(-)-N-Propargyl-1-aminoindan mesylate
CAS Number: 202464-88-8
Molecular Formula: C₁₃H₁₇NO₃S
Molecular Weight: 267.34400
Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
Create Date: 2018-06-02 23:35:30
Modify Date: 2024-01-11 22:05:30
TVP1022 mesylate is the S-isomer of rasagiline, which is an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor.

Name	S-(-)-N-Propargyl-1-aminoindan mesylate
Synonyms	TVP1022 (mesylate)

Description	TVP1022 mesylate is the S-isomer of rasagiline, which is an anti-Parkinson drug, appears to have the same neuroprotective activity as the R-isomer, but is 1000-fold less active as an MAO-B inhibitor.
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
References	[1]. Ertracht O, et al. The cardioprotective efficacy of TVP1022 in a rat model of ischaemia/reperfusion. Br J Pharmacol. 2011 Jun;163(4):755-69. [2]. Berdichevski A, et al. TVP1022 protects neonatal rat ventricular myocytes against doxorubicin-induced functional derangements. J Pharmacol Exp Ther. 2010 Feb;332(2):413-20.