PF 06465469

Modify Date: 2024-01-02 12:58:16

PF 06465469 Structure
PF 06465469 structure
Common Name PF 06465469
CAS Number 1407966-77-1 Molecular Weight 523.63
Density N/A Boiling Point N/A
Molecular Formula C30H33N7O2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of PF 06465469


PF-06465469 is a covalent inhibitor of ITK with an IC50 of 2 nM[1].

 Names

Name 3-{1-[(3R)-1-Acryloyl-3-piperidinyl]-4-amino-1H-pyrazolo[3,4-d]py rimidin-3-yl}-N-(4-isopropyl-3-methylphenyl)benzamide
Synonym More Synonyms

 PF 06465469 Biological Activity

Description PF-06465469 is a covalent inhibitor of ITK with an IC50 of 2 nM[1].
Related Catalog
Target

IC50: 2 nM (ITK)[1]

References

[1]. Mamand S, et al. Comparison of interleukin-2-inducible kinase (ITK) inhibitors and potential for combination therapies for T-cell lymphoma. Sci Rep. 2018 Sep 21;8(1):14216.

 Chemical & Physical Properties

Molecular Formula C30H33N7O2
Molecular Weight 523.63
Exact Mass 523.27000
PSA 119.03000
LogP 5.70120

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
RIDADR NONH for all modes of transport

 Synonyms

pf-06465469
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: PF-06465469
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao


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