1407966-77-1
1407966-77-1 structure
- Name: PF 06465469
- Chemical Name: 3-{1-[(3R)-1-Acryloyl-3-piperidinyl]-4-amino-1H-pyrazolo[3,4-d]py rimidin-3-yl}-N-(4-isopropyl-3-methylphenyl)benzamide
- CAS Number: 1407966-77-1
- Molecular Formula: C30H33N7O2
- Molecular Weight: 523.63
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Itk
- Create Date: 2016-05-19 22:44:28
- Modify Date: 2024-01-02 12:58:16
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PF-06465469 is a covalent inhibitor of ITK with an IC50 of 2 nM[1].
| Name | 3-{1-[(3R)-1-Acryloyl-3-piperidinyl]-4-amino-1H-pyrazolo[3,4-d]py rimidin-3-yl}-N-(4-isopropyl-3-methylphenyl)benzamide |
|---|---|
| Synonyms | pf-06465469 |
| Description | PF-06465469 is a covalent inhibitor of ITK with an IC50 of 2 nM[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 2 nM (ITK)[1] |
| References |
| Molecular Formula | C30H33N7O2 |
|---|---|
| Molecular Weight | 523.63 |
| Exact Mass | 523.27000 |
| PSA | 119.03000 |
| LogP | 5.70120 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |