PI3K-IN-38 structure
|
Common Name | PI3K-IN-38 | ||
|---|---|---|---|---|
| CAS Number | 1382979-64-7 | Molecular Weight | 380.44 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H24N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PI3K-IN-38PI3K-IN-38 (compound 123) is an orally active PI3K inhibitor with IC50 of 0.541 µM (PI3K-α). PI3K-IN-38 shows activities of anticancer and anti-inflammatory, which inhibis tumor growth in vivo[1]. |
| Name | PI3K-IN-38 |
|---|
| Description | PI3K-IN-38 (compound 123) is an orally active PI3K inhibitor with IC50 of 0.541 µM (PI3K-α). PI3K-IN-38 shows activities of anticancer and anti-inflammatory, which inhibis tumor growth in vivo[1]. |
|---|---|
| Related Catalog | |
| Target |
p110α:0.541 μM (IC50) |
| References |
[1]. Dotson J, et al. Tricyclic pi3k inhibitor compounds and methods of use. WO2012082997A1. |
| Molecular Formula | C20H24N6O2 |
|---|---|
| Molecular Weight | 380.44 |
| InChIKey | ZXKUIDJEEORBPY-UHFFFAOYSA-N |
| SMILES | CC1(C)OCCn2c1nc1c(N3CCOCC3)nc(-c3ccc(N)cc3)nc12 |