PI3K-IN-38

Modify Date: 2025-08-25 10:13:10

PI3K-IN-38 Structure
PI3K-IN-38 structure
Common Name PI3K-IN-38
CAS Number 1382979-64-7 Molecular Weight 380.44
Density N/A Boiling Point N/A
Molecular Formula C20H24N6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PI3K-IN-38


PI3K-IN-38 (compound 123) is an orally active PI3K inhibitor with IC50 of 0.541 µM (PI3K-α). PI3K-IN-38 shows activities of anticancer and anti-inflammatory, which inhibis tumor growth in vivo[1].

 Names

Name PI3K-IN-38

 PI3K-IN-38 Biological Activity

Description PI3K-IN-38 (compound 123) is an orally active PI3K inhibitor with IC50 of 0.541 µM (PI3K-α). PI3K-IN-38 shows activities of anticancer and anti-inflammatory, which inhibis tumor growth in vivo[1].
Related Catalog
Target

p110α:0.541 μM (IC50)

References

[1]. Dotson J, et al. Tricyclic pi3k inhibitor compounds and methods of use. WO2012082997A1.

 Chemical & Physical Properties

Molecular Formula C20H24N6O2
Molecular Weight 380.44
InChIKey ZXKUIDJEEORBPY-UHFFFAOYSA-N
SMILES CC1(C)OCCn2c1nc1c(N3CCOCC3)nc(-c3ccc(N)cc3)nc12
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