PI3K-IN-38

Names

[ Name ]:
PI3K-IN-38

Biological Activity

[Description]:

PI3K-IN-38 (compound 123) is an orally active PI3K inhibitor with IC50 of 0.541 µM (PI3K-α). PI3K-IN-38 shows activities of anticancer and anti-inflammatory, which inhibis tumor growth in vivo[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PI3K/Akt/mTOR >> PI3K

Research Areas >> Inflammation/Immunology

[Target]

p110α:0.541 μM (IC50)

[References]

[1]. Dotson J, et al. Tricyclic pi3k inhibitor compounds and methods of use. WO2012082997A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₄N₆O₂

[ Molecular Weight ]:
380.44

Related Compounds

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