DC Chemicals Limited
China
Product Name: PI3K-IN-30
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

2281803-22-1

2281803-22-1 structure

2281803-22-1 structure

Name: PI3K-IN-30
Chemical Name: PI3K-IN-30
CAS Number: 2281803-22-1
Molecular Formula: C₂₀H₂₅F₂N₇O₃
Molecular Weight: 449.45
Create Date: 2022-05-15 17:40:17
Modify Date: 2024-01-09 18:58:32
PI3K-IN-30 (compound 6d) is a potent PI3K inhibitor with IC50s of 5.1, 136, 30.7 and 8.9 nM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively[1].

Name	PI3K-IN-30

Description	PI3K-IN-30 (compound 6d) is a potent PI3K inhibitor with IC50s of 5.1, 136, 30.7 and 8.9 nM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> PI3K
Target	PI3Kα:5.1 nM (IC50) PI3Kβ:136 nM (IC50) PI3Kγ:30.7 nM (IC50) PI3Kδ:8.9 nM (IC50)
References	[1]. Van Dort ME, et al. Structural effects of morpholine replacement in ZSTK474 on Class I PI3K isoform inhibition: Development of novel MEK/PI3K bifunctional inhibitors. Eur J Med Chem. 2022;229:113996.

Molecular Formula	C₂₀H₂₅F₂N₇O₃
Molecular Weight	449.45