ponasterone A structure
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Common Name | ponasterone A | ||
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CAS Number | 13408-56-5 | Molecular Weight | 464.635 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 640.5±55.0 °C at 760 mmHg | |
Molecular Formula | C27H44O6 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 355.2±28.0 °C |
Use of ponasterone APonasterone A (25-Deoxyecdysterone), an ecdysteroid, has strong affinity for the ecdysone receptor. Ponasterone A is a potent regulator of gene expression in cells and transgenic animals, enabling reporter genes to be turned on and off rapidly[1][2]. |
Name | ponasterone A |
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Synonym | More Synonyms |
Description | Ponasterone A (25-Deoxyecdysterone), an ecdysteroid, has strong affinity for the ecdysone receptor. Ponasterone A is a potent regulator of gene expression in cells and transgenic animals, enabling reporter genes to be turned on and off rapidly[1][2]. |
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Related Catalog | |
Target |
ecdysone receptor[2] |
In Vitro | Ponasterone A (1 nM-100 μM) shows significant gene induction activity in CV-1 cells[2]. |
In Vivo | Ponasterone A (3-10 mg; i.p.) produces robust inductions of gene expression in transactivator and reporter mice[2]. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 640.5±55.0 °C at 760 mmHg |
Molecular Formula | C27H44O6 |
Molecular Weight | 464.635 |
Flash Point | 355.2±28.0 °C |
Exact Mass | 464.313782 |
PSA | 118.22000 |
LogP | 1.55 |
Vapour Pressure | 0.0±4.3 mmHg at 25°C |
Index of Refraction | 1.582 |
Storage condition | −20°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | Xi |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
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Genome-wide promoter binding profiling of protein phosphatase-1 and its major nuclear targeting subunits.
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25-Deoxyecdysterone |
(2b,3b,5b,22R)-2,3,14,20,22-Pentahydroxycholest-7-en-6-one |
ponasterone A |
(2β,3β,5β,22R)-2,3,14,20,22-Pentahydroxycholest-7-en-6-one |
Cholest-7-en-6-one, 2,3,14,20,22-pentahydroxy-, (2β,3β,5β,22R)- |
25-Deoxy-20-hydroxyecdysone |
MFCD00272144 |
(2S,3R,5R,9R,10R,13R,14S,17S)-17-[(2R,3R)-2,3-dihydroxy-6-methylheptan-2-yl]-2,3,14-trihydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one |