LY 2812223

Modify Date: 2024-01-10 18:06:40

LY 2812223 structure	Common Name	LY 2812223
	CAS Number	1311385-20-2	Molecular Weight	284.29
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₀H₁₂N₄O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of LY 2812223

LY2812223 is a highly potent, functionally selective mGlu2 receptor agonist with mGlu2 binding affinity for mGlu2 and mGlu2 (Ki=144 nM and 156 nM, respectively)[1].

Name	LY2812223

Description	LY2812223 is a highly potent, functionally selective mGlu2 receptor agonist with mGlu2 binding affinity for mGlu2 and mGlu2 (Ki=144 nM and 156 nM, respectively)[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGluR2:144 nM (Ki) mGluR3:156 nM (Ki)
References	[1]. Monn JA, et al. Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist. J Med Chem. 2015 Sep 24;58(18):7526-48.

Molecular Formula	C₁₀H₁₂N₄O₄S
Molecular Weight	284.29

DC Chemicals Limited
China
Product Name: LY 2812223
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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