Shanghai Nianxing Industrial Co., Ltd
China
Product Name: LY2812223
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: LY 2812223
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: LY 2812223
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

1311385-20-2

1311385-20-2 structure

1311385-20-2 structure

Name: LY 2812223
Chemical Name: LY2812223
CAS Number: 1311385-20-2
Molecular Formula: C₁₀H₁₂N₄O₄S
Molecular Weight: 284.29
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2019-08-03 17:13:58
Modify Date: 2025-08-26 18:51:27
LY2812223 is a highly potent, functionally selective mGlu2 receptor agonist with mGlu2 binding affinity for mGlu2 and mGlu2 (Ki=144 nM and 156 nM, respectively)[1].

Name	LY2812223

Description	LY2812223 is a highly potent, functionally selective mGlu2 receptor agonist with mGlu2 binding affinity for mGlu2 and mGlu2 (Ki=144 nM and 156 nM, respectively)[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGluR2:144 nM (Ki) mGluR3:156 nM (Ki)
References	[1]. Monn JA, et al. Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. Identification of (1R,2S,4R,5R,6R)-2-Amino-4-(1H-1,2,4-triazol-3-ylsulfanyl)bicyclo[3.1.0]hexane-2,6-dicarboxylic Acid (LY2812223), a Highly Potent, Functionally Selective mGlu2 Receptor Agonist. J Med Chem. 2015 Sep 24;58(18):7526-48.

Molecular Formula	C₁₀H₁₂N₄O₄S
Molecular Weight	284.29

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