APX-115 freebase

Modify Date: 2025-08-27 00:23:00

APX-115 freebase structure	Common Name	APX-115 freebase
	CAS Number	1270084-92-8	Molecular Weight	279.34
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₇N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of APX-115 freebase

APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 free base effectively prevents kidney injury[1].

Name	APX-115 free base

Description	APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 free base effectively prevents kidney injury[1].
Related Catalog	Research Areas >> Endocrinology
Target	Ki: 1.08 μM (Nox1), 0.57 μM (Nox2) and 0.63 μM (Nox4)[1]
References	[1]. Kwon G, et al. A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice: possible role of peroxisomal and mitochondrial biogenesis. Oncotarget. 2017 Jun 16;8(43):74217-74232.

Molecular Formula	C₁₇H₁₇N₃O
Molecular Weight	279.34

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: APX-115 freebase
Price: Check
Purity: 98.0%
Delivery: 10 Day
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: APX-115
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: APX-115
Price: $500.0/100mg $900.0/250mg $1800.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Price: ￥600/1 mg

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APX-115 freebase

Use of APX-115 freebase

Names

APX-115 freebase Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.