APX-115 freebase

Modify Date: 2024-01-10 14:17:22

APX-115 freebase structure	Common Name	APX-115 freebase
	CAS Number	1270084-92-8	Molecular Weight	279.34
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₁₇N₃O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of APX-115 freebase

APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 free base effectively prevents kidney injury[1].

Name	APX-115 free base

Description	APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively. APX-115 free base effectively prevents kidney injury[1].
Related Catalog	Research Areas >> Endocrinology
Target	Ki: 1.08 μM (Nox1), 0.57 μM (Nox2) and 0.63 μM (Nox4)[1]
References	[1]. Kwon G, et al. A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice: possible role of peroxisomal and mitochondrial biogenesis. Oncotarget. 2017 Jun 16;8(43):74217-74232.

Molecular Formula	C₁₇H₁₇N₃O
Molecular Weight	279.34

DC Chemicals Limited
China
Product Name: APX-115 freebase
Price: $500.0/100mg $900.0/250mg $1800.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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APX-115 freebase

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APX-115 freebase Biological Activity

Chemical & Physical Properties