BACE-IN-1

Modify Date: 2025-08-25 10:15:53

BACE-IN-1 Structure
BACE-IN-1 structure
Common Name BACE-IN-1
CAS Number 1254166-60-3 Molecular Weight 417.85
Density N/A Boiling Point N/A
Molecular Formula C22H16ClN5O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BACE-IN-1


BACE-IN-1 (Compound 13) is a substituted lmidazo[1 ,2-a]pyridine derivative which can inhibit β-site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment of diseases in which BACE is involved, such as Alzheimer's disease.

 Names

Name BACE-IN-1

 BACE-IN-1 Biological Activity

Description BACE-IN-1 (Compound 13) is a substituted lmidazo[1 ,2-a]pyridine derivative which can inhibit β-site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment of diseases in which BACE is involved, such as Alzheimer's disease.
Related Catalog
References

[1]. Adnan M.M. Mjalli, et al. SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE AS β-SECRETASE INHIBITORS. WO 2010126745 A1

 Chemical & Physical Properties

Molecular Formula C22H16ClN5O2
Molecular Weight 417.85
InChIKey XJBUEKXIUDQBPI-UHFFFAOYSA-N
SMILES O=C(Nc1nc2ccc(OCc3ccccc3)cc2[nH]1)c1cn2cc(Cl)ccc2n1
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