d-Corlin

Modify Date: 2025-08-20 14:25:34

d-Corlin structure	Common Name	d-Corlin
	CAS Number	125-10-0	Molecular Weight	400.46
	Density	1.3±0.1 g/cm3	Boiling Point	582.0±50.0 °C at 760 mmHg
	Molecular Formula	C₂₃H₂₈O₆	Melting Point	240-242°C (dec.)
	MSDS	N/A	Flash Point	200.2±23.6 °C

Use of d-Corlin

Prednisone acetate (Prednisone 21-acetate), the acetate salt form of prednisolone, is a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties[1].

Name	cortancyl
Synonym	More Synonyms

Description	Prednisone acetate (Prednisone 21-acetate), the acetate salt form of prednisolone, is a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor
Target	glucocorticoid receptor[1]
References	[1]. Prednisolone acetate

Density	1.3±0.1 g/cm3
Boiling Point	582.0±50.0 °C at 760 mmHg
Melting Point	240-242°C (dec.)
Molecular Formula	C₂₃H₂₈O₆
Molecular Weight	400.46
Flash Point	200.2±23.6 °C
Exact Mass	400.188599
PSA	97.74000
LogP	2.66
Vapour Pressure	0.0±3.7 mmHg at 25°C
Index of Refraction	1.580
Storage condition	Refrigerator

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU4154085

CHEMICAL NAME :: Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-, 21-acetate

CAS REGISTRY NUMBER :: 125-10-0

BEILSTEIN REFERENCE NO. :: 2342061

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C23-H28-O6

MOLECULAR WEIGHT :: 400.51

WISWESSER LINE NOTATION :: L E5 B666 CV OV AHTTT&J A1 E1 FV1OV1 FQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 330 mg/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue)

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 56,23,1980

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 135 mg/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 56,23,1980 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3270 No. of Facilities: 18 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1045 (estimated) No. of Female Employees: 1045 (estimated)

Hazard Codes	Xi
Risk Phrases	R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Phrases	S26-S36/37/39
HS Code	2937210000

Prednisolone Acetate

CAS#:52-21-1

~99%

d-Corlin

CAS#:125-10-0

Literature: Lapitskaya, Margarita A.; Vasiljeva, Ljudmila L.; Pivnitsky, Kasimir K. Mendeleev Communications, 2008 , vol. 18, # 6 p. 309 - 311

prednisolone

CAS#:50-24-8

d-Corlin

CAS#:125-10-0

Literature: Journal of the American Chemical Society, , vol. 77, p. 4781,4783

(17Z)-11beta,21...

CAS#:28449-43-6

d-Corlin

CAS#:125-10-0

Literature: Journal of the American Chemical Society, , vol. 77, p. 4436

Cortisone acetate

CAS#:50-04-4

d-Corlin

CAS#:125-10-0

Literature: Helvetica Chimica Acta, , vol. 39, p. 734,741 Recueil des Travaux Chimiques des Pays-Bas, , vol. 75, p. 475,480

Prednisone

CAS#:53-03-2

Ethanoic anhydride

CAS#:108-24-7

d-Corlin

CAS#:125-10-0

Literature: Heterocyclic Communications, , vol. 9, # 6 p. 575 - 578

Prednisolone Acetate

CAS#:52-21-1

(8S,9S,10R,11S,...

CAS#:898-84-0

d-Corlin

CAS#:125-10-0

Literature: Journal of Pharmaceutical Sciences, , vol. 72, # 1 p. 30 - 35

Precursor 6
CAS#:52-21-1 Prednisolone Acetate CAS#:50-24-8 prednisolone CAS#:28449-43-6 (17Z)-11beta,21... CAS#:50-04-4 Cortisone acetate
CAS#:53-03-2 Prednisone CAS#:108-24-7 Ethanoic anhydride
DownStream 3
CAS#:3044-42-6 21-Acetoxy-11be... CAS#:17652-24-3 [2-[(8S,9S,10R,... CAS#:53-03-2 Prednisone

HS Code	2937210000

d-Corlin

δ-Cortelan

Pregna-1,4-diene-3,11,20-trione, 21- (acetyloxy)-17-hydroxy-

Prednisone 21-acetate

EINECS 204-726-0

17-Hydroxy-3,11,20-trioxopregna-1,4-dien-21-yl acetate

Pregna-1,4-diene-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-

δ-Corlin

d-Cortelan

MFCD00200229

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: d-Corlin
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Prednisone acetate
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Prednisone 21-acetate
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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d-Corlin

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d-Corlin Biological Activity

Chemical & Physical Properties

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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Synthetic Route

Precursor & DownStream

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.