Tos-PEG4-methyl ester

Modify Date: 2024-01-12 19:05:35

Tos-PEG4-methyl ester Structure
Tos-PEG4-methyl ester structure
Common Name Tos-PEG4-methyl ester
CAS Number 1239588-09-0 Molecular Weight 390.45
Density N/A Boiling Point N/A
Molecular Formula C17H26O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tos-PEG4-methyl ester


Tos-PEG3-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Tos-PEG3-C2-methyl ester
Synonym More Synonyms

 Tos-PEG4-methyl ester Biological Activity

Description Tos-PEG3-C2-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C17H26O8S
Molecular Weight 390.45

 Synonyms

MFCD28967602