LSD1-IN-12

Modify Date: 2024-01-10 08:37:14

LSD1-IN-12 Structure
LSD1-IN-12 structure
Common Name LSD1-IN-12
CAS Number 1228143-76-7 Molecular Weight 252.31
Density N/A Boiling Point N/A
Molecular Formula C16H16N2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LSD1-IN-12


LSD1-IN-12 (compound 2) is a potent LSD1 inhibitor, with Ki values of 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), and 3.5 μM (MAO-B), respectively[1].

 Names

Name LSD1-IN-12

 LSD1-IN-12 Biological Activity

Description LSD1-IN-12 (compound 2) is a potent LSD1 inhibitor, with Ki values of 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), and 3.5 μM (MAO-B), respectively[1].
Related Catalog
Target

MAO-A:2.3 μM (Ki)

MAO-B:3.5 μM (Ki)

References

[1]. Li C, et al. Structure-Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors. J Med Chem. 2022 Mar 10;65(5):4335-4349.

 Chemical & Physical Properties

Molecular Formula C16H16N2O
Molecular Weight 252.31