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1228143-76-7

1228143-76-7 structure

1228143-76-7 structure

Name: LSD1-IN-12
Chemical Name: LSD1-IN-12
CAS Number: 1228143-76-7
Molecular Formula: C₁₆H₁₆N₂O
Molecular Weight: 252.31
Catalog: Signaling Pathways Epigenetics Histone Demethylase
Create Date: 2022-06-26 08:31:13
Modify Date: 2025-09-03 23:56:11
LSD1-IN-12 (compound 2) is a potent LSD1 inhibitor, with Ki values of 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), and 3.5 μM (MAO-B), respectively[1].

Name	LSD1-IN-12

Description	LSD1-IN-12 (compound 2) is a potent LSD1 inhibitor, with Ki values of 1.1 μM (LSD1), 61 μM (LSD2), 2.3 μM (MAO-A), and 3.5 μM (MAO-B), respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Demethylase Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase
Target	MAO-A:2.3 μM (Ki) MAO-B:3.5 μM (Ki)
References	[1]. Li C, et al. Structure-Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors. J Med Chem. 2022 Mar 10;65(5):4335-4349.

Molecular Formula	C₁₆H₁₆N₂O
Molecular Weight	252.31

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