ML133 HCl

Modify Date: 2025-08-24 20:26:09

ML133 HCl Structure
ML133 HCl structure
 Common Name ML133 HCl
CAS Number 1222781-70-5 Molecular Weight 313.82100
Density N/A Boiling Point N/A
Molecular Formula C19H20ClNO Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS05 GHS07 GHS09
GHS05, GHS07, GHS09		 Signal Word Danger

 Use of ML133 HCl


ML133 (hydrochloride) is a selective Kir2 family channels inhibitor, with an IC50 of 1.8 μM at pH 7.4 and 290 nM at pH 8.5[1].

 Names

Name 1-(4-methoxyphenyl)-N-(naphthalen-1-ylmethyl)methanamine,hydrochloride
Synonym More Synonyms

 ML133 HCl Biological Activity

Description ML133 (hydrochloride) is a selective Kir2 family channels inhibitor, with an IC50 of 1.8 μM at pH 7.4 and 290 nM at pH 8.5[1].
Related Catalog
Target

IC50: 1.8 μM (Kir2 at pH 7.4), 290 nM (Kir2 at pH 8.5)[1].

References

[1]. Wang HR, et al. Selective inhibition of the K(ir)2 family of inward rectifier potassium channels by a small molecule probe: the discovery, SAR, and pharmacological characterization of ML133. ACS Chem Biol. 2011 Aug 19;6(8):845-56.

 Chemical & Physical Properties

Molecular Formula C19H20ClNO
Molecular Weight 313.82100
Exact Mass 313.12300
PSA 21.26000
LogP 5.33110
Appearance of Characters white to tan
Storage condition 2-8°C
Water Solubility DMSO: ≥10mg/mL

 Safety Information

Symbol GHS05 GHS07 GHS09
GHS05, GHS07, GHS09
Signal Word Danger
Hazard Statements H302-H315-H318-H335-H400
Precautionary Statements P261-P273-P280-P305 + P351 + P338
Hazard Codes Xn,N
Risk Phrases 22-37/38-41-50/53
Safety Phrases 26-39-60-61
RIDADR UN 3077 9 / PGIII
HS Code 2922299090

 Customs

HS Code 2922299090
Summary 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

N-(4-methoxybenzyl)-1-(naphthalen-1-yl)methanamine hydrochloride
ML133 hydrochloride
ML133 HCL
1-Naphthalenemethanamine (N-[(4-methoxyphenyl)methyl]
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Chemsrc provides ML133 HCl(CAS#:1222781-70-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of ML133 HCl are included as well.>> amp version: ML133 HCl

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