2711717-77-8
2711717-77-8 structure
- Name: Difelikefalin HCl
- Chemical Name: Difelikefalin HCl
- CAS Number: 2711717-77-8
- Molecular Formula: C36H56Cl3N7O6
- Molecular Weight: 789.237
- Create Date: 2022-07-17 06:44:40
- Modify Date: 2024-01-09 13:48:25
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Difelikefalin is a κ-opioid receptor (KOR) agonist. It activates KOR in HEK293 cells expressing the human receptor (EC50 = 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50 = 0.048 nM). Difelikefalin is selective for KOR over the μ-opioid receptor.
| Name | Difelikefalin HCl |
|---|
| Description | Difelikefalin is a κ-opioid receptor (KOR) agonist. It activates KOR in HEK293 cells expressing the human receptor (EC50 = 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50 = 0.048 nM). Difelikefalin is selective for KOR over the μ-opioid receptor. |
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| Molecular Formula | C36H56Cl3N7O6 |
|---|---|
| Molecular Weight | 789.237 |