EGFR/HER2-IN-2

Modify Date: 2025-08-27 05:47:00

EGFR/HER2-IN-2 structure	Common Name	EGFR/HER2-IN-2
	CAS Number	1215571-02-0	Molecular Weight	453.49
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₃N₅O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of EGFR/HER2-IN-2

EGFR/HER2-IN-2 (Compound ZINC35560729) is a dual inhibitor of EGFR and HER2 with IC50 values of 5.02 µM and 0.83 µM against EGFR and HER2, respectively[1].

Name	EGFR/HER2-IN-2

Description	EGFR/HER2-IN-2 (Compound ZINC35560729) is a dual inhibitor of EGFR and HER2 with IC50 values of 5.02 µM and 0.83 µM against EGFR and HER2, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFR:5.02 μM (IC50) HER2:0.83 μM (IC50)
References	[1]. Sangande, et al. 2-substituted 4-aminoquinazoline derivatives as potential dual inhibitors of EGFR and HER2: an in silico and in vitro study. Medicinal Chemistry Research 31.5 (2022): 762-771.

Molecular Formula	C₂₆H₂₃N₅O₃
Molecular Weight	453.49

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