1215571-02-0

1215571-02-0 structure
1215571-02-0 structure
  • Name: EGFR/HER2-IN-2
  • Chemical Name: EGFR/HER2-IN-2
  • CAS Number: 1215571-02-0
  • Molecular Formula: C26H23N5O3
  • Molecular Weight: 453.49
  • Catalog: Signaling Pathways JAK/STAT Signaling EGFR
  • Create Date: 2022-07-01 11:48:56
  • Modify Date: 2025-08-27 05:47:00
  • EGFR/HER2-IN-2 (Compound ZINC35560729) is a dual inhibitor of EGFR and HER2 with IC50 values of 5.02 µM and 0.83 µM against EGFR and HER2, respectively[1].

Name EGFR/HER2-IN-2
Description EGFR/HER2-IN-2 (Compound ZINC35560729) is a dual inhibitor of EGFR and HER2 with IC50 values of 5.02 µM and 0.83 µM against EGFR and HER2, respectively[1].
Related Catalog
Target

EGFR:5.02 μM (IC50)

HER2:0.83 μM (IC50)

References

[1]. Sangande, et al. 2-substituted 4-aminoquinazoline derivatives as potential dual inhibitors of EGFR and HER2: an in silico and in vitro study. Medicinal Chemistry Research 31.5 (2022): 762-771.

Molecular Formula C26H23N5O3
Molecular Weight 453.49
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