1215571-02-0

1215571-02-0 structure

1215571-02-0 structure

Name: EGFR/HER2-IN-2
Chemical Name: EGFR/HER2-IN-2
CAS Number: 1215571-02-0
Molecular Formula: C₂₆H₂₃N₅O₃
Molecular Weight: 453.49
Catalog: Signaling Pathways JAK/STAT Signaling EGFR
Create Date: 2022-07-01 11:48:56
Modify Date: 2024-01-15 19:10:31
EGFR/HER2-IN-2 (Compound ZINC35560729) is a dual inhibitor of EGFR and HER2 with IC50 values of 5.02 µM and 0.83 µM against EGFR and HER2, respectively[1].

Name	EGFR/HER2-IN-2

Description	EGFR/HER2-IN-2 (Compound ZINC35560729) is a dual inhibitor of EGFR and HER2 with IC50 values of 5.02 µM and 0.83 µM against EGFR and HER2, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
Target	EGFR:5.02 μM (IC50) HER2:0.83 μM (IC50)
References	[1]. Sangande, et al. 2-substituted 4-aminoquinazoline derivatives as potential dual inhibitors of EGFR and HER2: an in silico and in vitro study. Medicinal Chemistry Research 31.5 (2022): 762-771.

Molecular Formula	C₂₆H₂₃N₅O₃
Molecular Weight	453.49