SN-38 GLUCURONIDE

Modify Date: 2025-08-25 19:52:24

SN-38 GLUCURONIDE Structure
SN-38 GLUCURONIDE structure
Common Name SN-38 GLUCURONIDE
CAS Number 121080-63-5 Molecular Weight 568.529
Density 1.7±0.1 g/cm3 Boiling Point 1019.7±65.0 °C at 760 mmHg
Molecular Formula C28H28N2O11 Melting Point N/A
MSDS N/A Flash Point 570.5±34.3 °C

 Use of SN-38 GLUCURONIDE


SN-38 glucuronide is an inactive metabolite of the cancer drug Irinotecan. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer[1].

 Names

Name SN-38 Glucuronide
Synonym More Synonyms

 SN-38 GLUCURONIDE Biological Activity

Description SN-38 glucuronide is an inactive metabolite of the cancer drug Irinotecan. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer[1].
Related Catalog
References

[1]. Pellock SJ, et al. Three structurally and functionally distinct β-glucuronidases from the human gut microbe Bacteroides uniformis. J Biol Chem. 2018;293(48):18559-18573.

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 1019.7±65.0 °C at 760 mmHg
Molecular Formula C28H28N2O11
Molecular Weight 568.529
Flash Point 570.5±34.3 °C
Exact Mass 568.169312
PSA 197.87000
LogP -0.28
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.746
InChIKey SSJQVDUAKDRWTA-CAYKMONMSA-N
SMILES CCc1c2c(nc3ccc(OC4OC(C(=O)O)C(O)C(O)C4O)cc13)-c1cc3c(c(=O)n1C2)COC(=O)C3(O)CC

 Synonyms

(4S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl β-D-glucopyranosiduronic acid
sn-38 glucuronide
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,11-diethyl-9-(β-D-glucopyranuronosyloxy)-4-hydroxy-, (4S)-
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