121080-63-5

121080-63-5 structure
121080-63-5 structure
  • Name: SN-38 GLUCURONIDE
  • Chemical Name: SN-38 Glucuronide
  • CAS Number: 121080-63-5
  • Molecular Formula: C28H28N2O11
  • Molecular Weight: 568.529
  • Catalog: Research Areas Cancer
  • Create Date: 2017-10-14 03:08:41
  • Modify Date: 2025-08-25 19:52:24
  • SN-38 glucuronide is an inactive metabolite of the cancer drug Irinotecan. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer[1].

Name SN-38 Glucuronide
Synonyms (4S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl β-D-glucopyranosiduronic acid
sn-38 glucuronide
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,11-diethyl-9-(β-D-glucopyranuronosyloxy)-4-hydroxy-, (4S)-
Description SN-38 glucuronide is an inactive metabolite of the cancer drug Irinotecan. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer[1].
Related Catalog
References

[1]. Pellock SJ, et al. Three structurally and functionally distinct β-glucuronidases from the human gut microbe Bacteroides uniformis. J Biol Chem. 2018;293(48):18559-18573.

Density 1.7±0.1 g/cm3
Boiling Point 1019.7±65.0 °C at 760 mmHg
Molecular Formula C28H28N2O11
Molecular Weight 568.529
Flash Point 570.5±34.3 °C
Exact Mass 568.169312
PSA 197.87000
LogP -0.28
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.746
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