121080-63-5

121080-63-5 structure

Name: SN-38 GLUCURONIDE
Chemical Name: SN-38 Glucuronide
CAS Number: 121080-63-5
Molecular Formula: C₂₈H₂₈N₂O₁₁
Molecular Weight: 568.529
Catalog: Research Areas Cancer
Create Date: 2017-10-14 03:08:41
Modify Date: 2024-01-02 09:02:04
SN-38 glucuronide is an inactive metabolite of the cancer drug Irinotecan. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer[1].

Name	SN-38 Glucuronide
Synonyms	(4S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl β-D-glucopyranosiduronic acid sn-38 glucuronide 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4,11-diethyl-9-(β-D-glucopyranuronosyloxy)-4-hydroxy-, (4S)-

Description	SN-38 glucuronide is an inactive metabolite of the cancer drug Irinotecan. Irinotecan is a topoisomerase I inhibitor which can be used for researching colon and rectal cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Pellock SJ, et al. Three structurally and functionally distinct β-glucuronidases from the human gut microbe Bacteroides uniformis. J Biol Chem. 2018;293(48):18559-18573.