TRANS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID

Modify Date: 2024-01-01 21:50:25

TRANS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID structure	Common Name	TRANS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID
	CAS Number	117488-23-0	Molecular Weight	159.14000
	Density	1.568g/cm3	Boiling Point	288.1ºC at 760mmHg
	Molecular Formula	C₆H₉NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	128ºC

Use of TRANS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID

trans-ACBD (trans-1-Aminocyclobutane-1,3-dicarboxylic acid) is a very potent and selective NMDA receptor agonist that modulates glutamatergic neurotransmission[1].

Name	1-aminocyclobutane-cis-1,3-dicarboxylic acid
Synonym	More Synonyms

Description	trans-ACBD (trans-1-Aminocyclobutane-1,3-dicarboxylic acid) is a very potent and selective NMDA receptor agonist that modulates glutamatergic neurotransmission[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. Dimpfel W, et al. Effects of rasagiline, its metabolite aminoindan and selegiline on glutamate receptor mediated signalling in the rat hippocampus slice in vitro. BMC Pharmacol. 2011 Feb 21;11:2.

Density	1.568g/cm3
Boiling Point	288.1ºC at 760mmHg
Molecular Formula	C₆H₉NO₄
Molecular Weight	159.14000
Flash Point	128ºC
Exact Mass	159.05300
PSA	100.62000
Vapour Pressure	0.000607mmHg at 25°C
Index of Refraction	1.587

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GU1690000

CHEMICAL NAME :: 1,3-Cyclobutanedicarboxylic acid, 1-amino-, trans-, hydrate

CAS REGISTRY NUMBER :: 117488-23-0

LAST UPDATED :: 199109

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C6-H9-N-O4.H2-O

MOLECULAR WEIGHT :: 177.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 33,2905,1990

trans-1-aminocyclobutane-1,3-dicarboxylic acid

cis-2,4-methanoglutamate

1-aminocyclobutyl carboxylic acid methyl ester

1-AMINO-CYCLOBUTANECARBOXYLIC ACID METHYL ESTER

trans-2,4-methanoglutamic acid

methyl 1-amino-cyclobutanecarboxylate

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: TRANS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

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