TRANS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID

Modify Date: 2025-08-26 16:21:52

TRANS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID structure	Common Name	TRANS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID
	CAS Number	117488-23-0	Molecular Weight	159.14000
	Density	1.568g/cm3	Boiling Point	288.1ºC at 760mmHg
	Molecular Formula	C₆H₉NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	128ºC

Use of TRANS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID

trans-ACBD (trans-1-Aminocyclobutane-1,3-dicarboxylic acid) is a very potent and selective NMDA receptor agonist that modulates glutamatergic neurotransmission[1].

Name	1-aminocyclobutane-cis-1,3-dicarboxylic acid
Synonym	More Synonyms

Description	trans-ACBD (trans-1-Aminocyclobutane-1,3-dicarboxylic acid) is a very potent and selective NMDA receptor agonist that modulates glutamatergic neurotransmission[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
References	[1]. Dimpfel W, et al. Effects of rasagiline, its metabolite aminoindan and selegiline on glutamate receptor mediated signalling in the rat hippocampus slice in vitro. BMC Pharmacol. 2011 Feb 21;11:2.

Density	1.568g/cm3
Boiling Point	288.1ºC at 760mmHg
Molecular Formula	C₆H₉NO₄
Molecular Weight	159.14000
Flash Point	128ºC
Exact Mass	159.05300
PSA	100.62000
Vapour Pressure	0.000607mmHg at 25°C
Index of Refraction	1.587

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GU1690000

CHEMICAL NAME :: 1,3-Cyclobutanedicarboxylic acid, 1-amino-, trans-, hydrate

CAS REGISTRY NUMBER :: 117488-23-0

LAST UPDATED :: 199109

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C6-H9-N-O4.H2-O

MOLECULAR WEIGHT :: 177.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 33,2905,1990

trans-1-aminocyclobutane-1,3-dicarboxylic acid

cis-2,4-methanoglutamate

1-aminocyclobutyl carboxylic acid methyl ester

1-AMINO-CYCLOBUTANECARBOXYLIC ACID METHYL ESTER

trans-2,4-methanoglutamic acid

methyl 1-amino-cyclobutanecarboxylate

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Trans-ACBD
Price: Check
Purity: 99.75%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: TRANS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Use of TRANS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID

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Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.