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73550-55-7

73550-55-7 structure
73550-55-7 structure
  • Name: cis-ABCD
  • Chemical Name: cis-ACBD,cis-1-Aminocyclobutane-1,3-dicarboxylicacid
  • CAS Number: 73550-55-7
  • Molecular Formula: C6H9NO4
  • Molecular Weight: 159.14000
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2018-12-15 17:38:29
  • Modify Date: 2024-01-05 11:27:10
  • cis-ACBD is a potent and selective inhibitor of the high-affinity, Na+-dependent plasma membrane glutamate transporter. cis-ACBD is a glutamate reuptake inhibitor. cis-ACBD also acts as linear competitive inhibitor of the uptake of D-[3H]aspartate[1][2].
Name cis-ACBD,cis-1-Aminocyclobutane-1,3-dicarboxylicacid
Synonyms CIS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID
5-Methylfurmethiodide
TRANS-1-AMINOCYCLOBUTANE-1,3-DICARBOXYLIC ACID
CIS-2,4-METHANOGLUTAMIC ACID
CIS-ACBD
cis-1-Aminocyclobutan-1,3-dicarboxylic acid
1-amino-1,3-dicarboxycyclobutane
trans-2,4-methanoglutamic acid
1-AMINOCYCLOBUTANE-TRANS-1,3-DICARBOXYLIC ACID
2-methanoglutamic acid
cis-1-amino-1,3-cyclobutanedicarboxylicacid
TRANS-ACBD
Description cis-ACBD is a potent and selective inhibitor of the high-affinity, Na+-dependent plasma membrane glutamate transporter. cis-ACBD is a glutamate reuptake inhibitor. cis-ACBD also acts as linear competitive inhibitor of the uptake of D-[3H]aspartate[1][2].
Related Catalog
References

[1]. Ai J, et al. Presynaptic excitability as a potential target for the treatment of the traumatic cerebellum. Pharmacology. 2004 Aug;71(4):192-8.

[2]. Griffiths R, et al. L-trans-pyrrolidine-2,4-dicarboxylate and cis-1-aminocyclobutane-1,3-dicarboxylate behave as transportable, competitive inhibitors of the high-affinity glutamate transporters. Biochem Pharmacol. 1994 Jan 20;47(2):267-74.
Density 1.568g/cm3
Boiling Point 288.1ºC at 760 mmHg
Molecular Formula C6H9NO4
Molecular Weight 159.14000
Flash Point 128ºC
Exact Mass 159.05300
PSA 100.62000
Index of Refraction 1.587

CHEMICAL IDENTIFICATION

RTECS NUMBER :
GU1685000
CHEMICAL NAME :
1,3-Cyclobutanedicarboxylic acid, 1-amino-, cis-, hydrate
CAS REGISTRY NUMBER :
73550-55-7
LAST UPDATED :
199109
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H9-N-O4.H2-O
MOLECULAR WEIGHT :
177.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 33,2905,1990

Chemsrc provides CAS#:73550-55-7 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 73550-55-7 | Chemsrc address: https://www.chemsrc.com/en/baike/671806.html

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