NAN-190 hydrobromide

Modify Date: 2025-09-06 22:00:51

NAN-190 hydrobromide structure	Common Name	NAN-190 hydrobromide
	CAS Number	115338-32-4	Molecular Weight	474.39100
	Density	N/A	Boiling Point	560.8ºC at 760mmHg
	Molecular Formula	C₂₃H₂₈BrN₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	293ºC

Use of NAN-190 hydrobromide

NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist. NAN-190 is a selective antagonist of 5-HT1A.Target: 5-HT in vitro: NAN-190 is a 5-HT1A antagonist. [3] NAN-190 is a selective antagonist of 5-HT1A. [1]in vivo: NAN-190 (0.5 mg/kg, ip), as a 5-HT1A receptor antagonist, is injected concomitantly with the effective dose of fluoxetine. NAN-190 (5-HT1A receptor antagonist) reverses the catalepsy-improving effect of fluoxetine in 6-OHDA lesioned rats. [2]

Name	NAN 190 hydrobromide
Synonym	More Synonyms

Description	NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist. NAN-190 is a selective antagonist of 5-HT1A.Target: 5-HT in vitro: NAN-190 is a 5-HT1A antagonist. [3] NAN-190 is a selective antagonist of 5-HT1A. [1]in vivo: NAN-190 (0.5 mg/kg, ip), as a 5-HT1A receptor antagonist, is injected concomitantly with the effective dose of fluoxetine. NAN-190 (5-HT1A receptor antagonist) reverses the catalepsy-improving effect of fluoxetine in 6-OHDA lesioned rats. [2]
Related Catalog	Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor Research Areas >> Neurological Disease
References	[1]. Shahane SA, et al. Detection of phospholipidosis induction: a cell-based assay in high-throughput and high-content format. J Biomol Screen. 2014 Jan;19(1):66-76. [2]. Sharifi H, et al. Dose-Dependent Effect of Flouxetine on 6-OHDA-Induced Catalepsy in Male Rats: A Possible Involvement of 5-HT1A Receptors. Adv Pharm Bull. 2013;3(1):203-6. [3]. Citó MC, et al. Antidepressant-like effect of Hoodia gordonii in a forced swimming test in mice: evidence for involvement of the monoaminergic system. Braz J Med Biol Res. 2015 Jan;48(1):57-64.

Description

Related Catalog

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

Research Areas >> Neurological Disease

References

[1]. Shahane SA, et al. Detection of phospholipidosis induction: a cell-based assay in high-throughput and high-content format. J Biomol Screen. 2014 Jan;19(1):66-76.

[2]. Sharifi H, et al. Dose-Dependent Effect of Flouxetine on 6-OHDA-Induced Catalepsy in Male Rats: A Possible Involvement of 5-HT1A Receptors. Adv Pharm Bull. 2013;3(1):203-6.

[3]. Citó MC, et al. Antidepressant-like effect of Hoodia gordonii in a forced swimming test in mice: evidence for involvement of the monoaminergic system. Braz J Med Biol Res. 2015 Jan;48(1):57-64.

Boiling Point	560.8ºC at 760mmHg
Molecular Formula	C₂₃H₂₈BrN₃O₃
Molecular Weight	474.39100
Flash Point	293ºC
Exact Mass	473.13100
PSA	53.09000
LogP	3.79250
Vapour Pressure	1.32E-12mmHg at 25°C
Storage condition	2-8℃

Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	26-36
HS Code	2933599090

4-(1,3-DIOXOISO...

CAS#:3598-60-5

1-(2-Methoxyphe...

CAS#:5464-78-8

NAN-190 hydrobromide

CAS#:115338-32-4

Literature: Kowalski, Piotr; Jaskowska, Jolanta Archiv der Pharmazie, 2012 , vol. 345, # 1 p. 81 - 85

phthalimide

CAS#:136918-14-4

NAN-190 hydrobromide

CAS#:115338-32-4

Literature: Kowalski, Piotr; Jaskowska, Jolanta Archiv der Pharmazie, 2012 , vol. 345, # 1 p. 81 - 85

Precursor 2
CAS#:3598-60-5 4-(1,3-DIOXOISO... CAS#:5464-78-8 1-(2-Methoxyphe...
DownStream 0

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

1-(2-Methoxyphenyl)-4-[4-(2-phthalimido)butyl]piperazine hydrobromide

1-[2-METHOXYPHENYL]-4-[4-(2-PHTHALIMIDO)-BUTYL]PIPERAZINE HYDROCHLORIDE

NAN-190 HYDROCHLORIDE

NAN-190 HYDROBROMIDE

NAN-190 (hydrobromide)

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 1-[2-METHOXYPHENYL]-4-[4-(2-PHTHALIMIDO)-BUTYL]PIPERAZINEHYDROCHLORIDE
Price: Check
Purity: 99.0%
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DC Chemicals Limited
China
Product Name: NAN-190 hydrobromide
Price: $150.0/100mg $300.0/250mg $600.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: NAN-190 hydrobromide
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

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Price: $66/10mM*1mLinDMSO

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NAN-190 hydrobromide

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NAN-190 hydrobromide Biological Activity

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.