Mupirocin calcium hydrate
Modify Date: 2025-08-20 19:51:27
Mupirocin calcium hydrate structure
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Common Name | Mupirocin calcium hydrate | ||
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| CAS Number | 115074-43-6 | Molecular Weight | 1075.34000 | |
| Density | N/A | Boiling Point | 672.3ºC at 760 mmHg | |
| Molecular Formula | C26H44O9.1/2Ca.H2O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 216.5ºC | |
Use of Mupirocin calcium hydrateMupirocin calcium hydrate is an orally active antibiotic isolated from Pseudomonas fluorescens. Mupirocin calcium hydrate apparently exerts its antimicrobial activity by reversibly inhibiting isoleucyl-transfer RNA, thereby inhibiting bacterial protein and RNA synthesis[1][2]. |
| Name | mupirocin calcium, reference spectrum ep standard |
|---|---|
| Synonym | More Synonyms |
| Description | Mupirocin calcium hydrate is an orally active antibiotic isolated from Pseudomonas fluorescens. Mupirocin calcium hydrate apparently exerts its antimicrobial activity by reversibly inhibiting isoleucyl-transfer RNA, thereby inhibiting bacterial protein and RNA synthesis[1][2]. |
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| Related Catalog | |
| In Vitro | Mupirocin Calcium Salt shows a high level of activity against staphylococci and streptococci and against certain gram-negative bacteria. Mupirocin Calcium Salt is highly bound (95% bound) to the protein of human serum, and activity was reduced 10- to 20-fold in the presence of human serum[1]. |
| In Vivo | Mupirocin Calcium Salt is well absorbed after oral and parenteral administration but serum antibiotic concentrations were short-lived as a result of extensive degradation to the antibacterially inactive metabolite, monic acid A[1]. |
| References |
| Boiling Point | 672.3ºC at 760 mmHg |
|---|---|
| Molecular Formula | C26H44O9.1/2Ca.H2O |
| Molecular Weight | 1075.34000 |
| Flash Point | 216.5ºC |
| Exact Mass | 1074.57000 |
| PSA | 288.56000 |
| LogP | 4.90220 |
| Vapour Pressure | 5.91E-21mmHg at 25°C |
| InChIKey | DDHVILIIHBIMQU-YJGQQKNPSA-L |
| SMILES | CC(=CC(=O)OCCCCCCCCC(=O)[O-])CC1OCC(CC2OC2C(C)C(C)O)C(O)C1O.CC(=CC(=O)OCCCCCCCCC(=O)[O-])CC1OCC(CC2OC2C(C)C(C)O)C(O)C1O.O.O.[Ca+2] |
| Storage condition | -20℃ |
| Water Solubility | Very slightly soluble in water, sparingly soluble in anhydrous ethanol and in methylene chloride. |
| RIDADR | NONH for all modes of transport |
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| Mupirocin calcium dihydrate |
| Unii-rg38I2p540 |
| MupirocinCalcium |
| mupirocin calcium hydrate |
| Calcium mupirocin dihydrate |
| Mupirocin Calcium Salt |