Calpain Inhibitor I
Calpain Inhibitor I structure
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Common Name | Calpain Inhibitor I | ||
|---|---|---|---|---|
| CAS Number | 110044-82-1 | Molecular Weight | 383.526 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 632.2±50.0 °C at 760 mmHg | |
| Molecular Formula | C20H37N3O4 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 192.9±30.3 °C | |
Use of Calpain Inhibitor IMG-101 is a potent inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively. |
| Name | acetylleucyl-leucyl-norleucinal |
|---|---|
| Synonym | More Synonyms |
| Description | MG-101 is a potent inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 632.2±50.0 °C at 760 mmHg |
| Molecular Formula | C20H37N3O4 |
| Molecular Weight | 383.526 |
| Flash Point | 192.9±30.3 °C |
| Exact Mass | 383.278412 |
| PSA | 104.37000 |
| LogP | 3.37 |
| Appearance of Characters | powder | white |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.474 |
| Storage condition | −20°C |
| Water Solubility | DMSO: soluble | Soluble in dimethyl sulfoxide, ethanol, methanol. Insoluble in water, and aqueous buffers. |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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Hook proteins: association with Alzheimer pathology and regulatory role of hook3 in amyloid beta generation.
PLoS ONE 10(3) , e0119423, (2015) Defects in intracellular transport are implicated in the pathogenesis of Alzheimer's disease (AD). Hook proteins are a family of cytoplasmic linker proteins that participate in endosomal transport. In... |
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The role of proteases in excitation-contraction coupling failure in muscular dystrophy.
Am. J. Physiol. Cell Physiol. 308(1) , C33-40, (2015) Duchenne muscular dystrophy (DMD) is one of the most frequent types of muscular dystrophy. Alterations in intracellular calcium (Ca(2+)) handling are thought to contribute to the disease severity in D... |
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Necrosis- and apoptosis-related Met cleavages have divergent functional consequences.
Cell Death Dis. 6 , e1769, (2015) Upon activation by its ligand hepatocyte growth factor/scatter factor, the receptor tyrosine kinase Met promotes survival, proliferation, and migration of epithelial cells during embryogenesis. Deregu... |
| N-Acetyl-L-leucyl-N-[(2S)-1-oxohexan-2-yl]-L-leucinamide |
| ALLN Ac-LLnL-CHO MG-101 N-Acetyl-Leu-Leu-Norleu-al N-Acetyl-L-leucyl-L-leucyl-L-norleucinal |
| Ac-Leu-Leu-Nle-H |
| AC-LL-NORLEUCINAL |
| AC-LEU-LEU-NORLEUCINAL |
| Ac-Leu-Leu-Nle-al |
| Calpain Inhibitor I,ALLN |
| CALPAIN INHIBITOR I |
| MG 101 |
| ALLN |
| N-Acetyl-L-leucyl-N-((1S)-1-formylpentyl)-L-leucinamide |
| ac-llnl-cho |
| AC-LEU-LEU-NLE-CHO |
| acetylleucyl-leucyl-norleucinal |
| N-Acetyl-L-leucyl-N-[(2S)-1-oxo-2-hexanyl]-L-leucinamide |
| L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-1-formylpentyl]- |
| LLNL |
| CALPAIN INHIBITOR |
| MFCD00065505 |
- DC Chemicals Limited
- China
- Product Name: MG-101
- Price: $550.0/100mg $950.0/250mg $1900.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: MG-101
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
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