Calpain Inhibitor VI

Modify Date: 2024-01-06 20:23:39

Calpain Inhibitor VI structure	Common Name	Calpain Inhibitor VI
	CAS Number	190274-53-4	Molecular Weight	372.455
	Density	1.2±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₇H₂₅FN₂O₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Calpain Inhibitor VI

Calpain Inhibitor VI (SJA6017) is a synthesized peptide aldehyde inhibitor of calpain. Calpain Inhibitor VI inhibits purified m-calpain with the IC50 of 80 nM. Calpain Inhibitor VI can be used for the research of cataract[1].

Name	2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-(4-methyl-1-oxopentan-2-yl)butanamide
Synonym	More Synonyms

Description	Calpain Inhibitor VI (SJA6017) is a synthesized peptide aldehyde inhibitor of calpain. Calpain Inhibitor VI inhibits purified m-calpain with the IC50 of 80 nM. Calpain Inhibitor VI can be used for the research of cataract[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome
References	[1]. C Fukiage, et al. SJA6017, a newly synthesized peptide aldehyde inhibitor of calpain: amelioration of cataract in cultured rat lenses. Biochim Biophys Acta. 1997 Oct 24;1361(3):304-12.

Density	1.2±0.1 g/cm3
Molecular Formula	C₁₇H₂₅FN₂O₄S
Molecular Weight	372.455
Exact Mass	372.151917
PSA	100.72000
LogP	3.21
Index of Refraction	1.512

(2S)-2-((4-fluo...

CAS#:438003-82-8

~60%

Calpain Inhibitor VI

CAS#:190274-53-4

Literature: Senju Pharmaceutical Co., Ltd. Patent: EP1557407 A1, 2005 ; Location in patent: Page/Page column 6 ;

methyl (2'S,2S)...

CAS#:797049-70-8

~74%

Calpain Inhibitor VI

CAS#:190274-53-4

Literature: Payne, Richard J.; Brown, Karina M.; Coxon, James M.; Morton, James D.; Lee, Hannah Yun-Young; Abell, Andrew D. Australian Journal of Chemistry, 2004 , vol. 57, # 9 p. 877 - 884

chloro(4-fluoro...

CAS#:349-88-2

Calpain Inhibitor VI

CAS#:190274-53-4

Literature: Inoue, Jun; Nakamura, Masayuki; Cui, Ying-She; Sakai, Yusuke; Sakai, Osamu; Hill, Jeanette R.; Wang, Kevin K. W.; Yuen, Po-Wai Journal of Medicinal Chemistry, 2003 , vol. 46, # 5 p. 868 - 871

L-Valine, N-[(4...

CAS#:97801-48-4

Calpain Inhibitor VI

CAS#:190274-53-4

L-Valine

CAS#:72-18-4

Calpain Inhibitor VI

CAS#:190274-53-4

N/A

CAS#:190275-58-2

Calpain Inhibitor VI

CAS#:190274-53-4

methyl ((4-fluo...

CAS#:797049-66-2

Calpain Inhibitor VI

CAS#:190274-53-4

Literature: Payne, Richard J.; Brown, Karina M.; Coxon, James M.; Morton, James D.; Lee, Hannah Yun-Young; Abell, Andrew D. Australian Journal of Chemistry, 2004 , vol. 57, # 9 p. 877 - 884

L-VALINE METHYL...

CAS#:4070-48-8

Calpain Inhibitor VI

CAS#:190274-53-4

Literature: Payne, Richard J.; Brown, Karina M.; Coxon, James M.; Morton, James D.; Lee, Hannah Yun-Young; Abell, Andrew D. Australian Journal of Chemistry, 2004 , vol. 57, # 9 p. 877 - 884

N-[(4-Fluorophenyl)sulfonyl]-N-[(2S)-4-methyl-1-oxo-2-pentanyl]-L-valinamide

N-((4-Fluorophenyl)sulfonyl)-L-valyl-L-leucinal

IN1503

Butanamide, 2-[[(4-fluorophenyl)sulfonyl]amino]-N-[(1S)-1-formyl-3-methylbutyl]-3-methyl-, (2S)-

(2R)-2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]butanamide

calpain inhibitor VI

4-fluorophenylsulfonyl-Val-Leu-CHO

(1'S,2S)-2-(4-fluorobenzenesulfonylamino)-N-(1-formyl-3-methylbutyl)-3-methylbutyramide