Shanghai Nianxing Industrial Co., Ltd
China
Product Name: CalpainInhibitorI
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: MG-101
Price: $550.0/100mg $950.0/250mg $1900.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: MG-101
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

110044-82-1

110044-82-1 structure

110044-82-1 structure

Name: Calpain Inhibitor I
Chemical Name: acetylleucyl-leucyl-norleucinal
CAS Number: 110044-82-1
Molecular Formula: C₂₀H₃₇N₃O₄
Molecular Weight: 383.526
Catalog: Biochemical Inhibitor Proteases Cysteine Protease Inhibitor
Create Date: 2018-06-23 18:43:41
Modify Date: 2025-08-20 09:35:42
MG-101 is a potent inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively.

Name	acetylleucyl-leucyl-norleucinal
Synonyms	N-Acetyl-L-leucyl-N-[(2S)-1-oxohexan-2-yl]-L-leucinamide ALLN Ac-LLnL-CHO MG-101 N-Acetyl-Leu-Leu-Norleu-al N-Acetyl-L-leucyl-L-leucyl-L-norleucinal Ac-Leu-Leu-Nle-H AC-LL-NORLEUCINAL AC-LEU-LEU-NORLEUCINAL Ac-Leu-Leu-Nle-al Calpain Inhibitor I,ALLN CALPAIN INHIBITOR I MG 101 ALLN N-Acetyl-L-leucyl-N-((1S)-1-formylpentyl)-L-leucinamide ac-llnl-cho AC-LEU-LEU-NLE-CHO acetylleucyl-leucyl-norleucinal N-Acetyl-L-leucyl-N-[(2S)-1-oxo-2-hexanyl]-L-leucinamide L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-1-formylpentyl]- LLNL CALPAIN INHIBITOR MFCD00065505

Description	MG-101 is a potent inhibitor of cysteine proteases which inhibits calpain I, calpain II, cathepsin B and cathepsin L with Kis of 190, 220, 150 and 500 pM, respectively.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome Research Areas >> Cancer
References	[1]. Li SZ, et al. ALLN hinders HCT116 tumor growth through Bax-dependent apoptosis. Biochem Biophys Res Commun. 2013 Jul 26;437(2):325-330.

Density	1.0±0.1 g/cm3
Boiling Point	632.2±50.0 °C at 760 mmHg
Molecular Formula	C₂₀H₃₇N₃O₄
Molecular Weight	383.526
Flash Point	192.9±30.3 °C
Exact Mass	383.278412
PSA	104.37000
LogP	3.37
Appearance	powder \| white
Vapour Pressure	0.0±1.9 mmHg at 25°C
Index of Refraction	1.474
Storage condition	−20°C
Water Solubility	DMSO: soluble \| Soluble in dimethyl sulfoxide, ethanol, methanol. Insoluble in water, and aqueous buffers.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	22-24/25
RIDADR	NONH for all modes of transport
WGK Germany	3

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