ALLM
Modify Date: 2025-08-25 20:53:05
ALLM structure
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Common Name | ALLM | ||
|---|---|---|---|---|
| CAS Number | 110115-07-6 | Molecular Weight | 401.564 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 676.5±55.0 °C at 760 mmHg | |
| Molecular Formula | C19H35N3O4S | Melting Point | N/A | |
| MSDS | Chinese | Flash Point | 362.9±31.5 °C | |
Use of ALLMALLM (Calpain inhibitor II) is a potent inhibitor of calpain and cathepsin proteases. ALLM inhibits neuronal cell death and improves chronic neurological function after spinal cord injury (SCI)[1][2]. |
| Name | calpain inhibitor ii |
|---|---|
| Synonym | More Synonyms |
| Description | ALLM (Calpain inhibitor II) is a potent inhibitor of calpain and cathepsin proteases. ALLM inhibits neuronal cell death and improves chronic neurological function after spinal cord injury (SCI)[1][2]. |
|---|---|
| Related Catalog | |
| In Vivo | ALLM (Calpain inhibitor II) (0.5 mg/kg) is injected every 24 h for 5 days after SCI and inhibits the activation of calpain but not that of caspase 3. ALLM prevents this neuronal cell death[2]. ALLM (0.05-2.5 mg/kg; i.p.; every 24 h for 1 week) reduces motor disturbances after spinal cord injury (SCI)[2]. Animal Model: Adult male Wistar rats (280-300g) (spinal cord injury model)[2] Dosage: 0.05, 0.5, and 2.5 mg/kg Administration: Intraperitoneally; every 24 h for 1 week Result: Showed significantly better motor function. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 676.5±55.0 °C at 760 mmHg |
| Molecular Formula | C19H35N3O4S |
| Molecular Weight | 401.564 |
| Flash Point | 362.9±31.5 °C |
| Exact Mass | 401.234833 |
| PSA | 129.67000 |
| LogP | 2.64 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.496 |
| Storage condition | −20°C |
| Water Solubility | Very slightly soluble (0.52 g/L) (25 ºC) |
| Hazard Codes | Xi |
|---|---|
| Safety Phrases | S22-S24/25 |
| WGK Germany | 3 |
| N-Acetyl-L-leucyl-N-[(2S)-4-(methylsulfanyl)-1-oxo-2-butanyl]-L-leucinamide |
| N-AC-LEU-LEU-METHIONINAL |
| AC-LEU-LEU-L-METHIONINAL |
| L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]- |
| Ac-Leu-Leu-Met-al |
| N-Acetyl-L-leucyl-N-[(2S)-4-(methylsulfanyl)-1-oxobutan-2-yl]-L-leucinamide |
| ALLM |
| AC-LEU-LEU-MET-ALDEHYDE |
| AC-LEU-LEU-METHIONINAL |
| AC-LEU-LEU-MET-CHO |
| N-ACETYL-LEU-LEU-MET-CHO |
| MFCD00065506 |
| AC-LLM-CHO |