Boc-Gln-Arg-Arg-AMC

Modify Date: 2024-01-02 12:07:01

Boc-Gln-Arg-Arg-AMC Structure
Boc-Gln-Arg-Arg-AMC structure
Common Name Boc-Gln-Arg-Arg-AMC
CAS Number 109376-05-8 Molecular Weight 715.80
Density N/A Boiling Point N/A
Molecular Formula C32H49N11O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Boc-Gln-Arg-Arg-AMC


Boc-Gln-Arg-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].

 Names

Name boc-gln-arg-arg-amc acetate salt
Synonym More Synonyms

 Boc-Gln-Arg-Arg-AMC Biological Activity

Description Boc-Gln-Arg-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].
Related Catalog
References

[1]. Tervonen TA, et, al. Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion. Oncogene. 2016 Apr 7;35(14):1832-46.  

 Chemical & Physical Properties

Molecular Formula C32H49N11O8
Molecular Weight 715.80
Exact Mass 715.37700
PSA 322.73000
LogP 4.02270

 Synonyms

Boc-Gln-Arg-Arg-7-amido-4-methylcoumarin acetate salt
BOC-GLN-ARG-ARG-AMC ACOH
T-BUTYLOXYCARBONYL-L-GLUTAMINYL-L-ARGINYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE
Boc-Gln-Arg-Arg-AMC
N-T-BOC-GLN-ARG-ARG 7-AMIDO-4-*METHYLCOUMARIN ACETAT
N-T-boc-gln-arg-arg 7-amido-4-*methylcoumarin ace
N-tert-BOC-Gln-Arg-Arg 7-amido-4-methylcoumarin acetate
BOC-GLN-ARG-ARG-MCA