109358-46-5
109358-46-5 structure
- Name: Boc-Leu-Arg-Arg-AMC · 2 HCl
- Chemical Name: Boc-Leu-Arg-Arg-AMC · 2 HCl
- CAS Number: 109358-46-5
- Molecular Formula: C33H52N10O7
- Molecular Weight: 700.829
- Create Date: 2018-09-16 12:10:29
- Modify Date: 2025-08-23 18:49:47
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Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core. Upon enzymatic cleavage by the 26S proteasome or 20S proteolytic core, amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify 26S proteasome or 20S proteolytic core trypsin-like activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
| Name | Boc-Leu-Arg-Arg-AMC · 2 HCl |
|---|---|
| Synonyms |
L-Argininamide, N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-leucyl-L-arginyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C33H52N10O7 |
| Molecular Weight | 700.829 |
| Exact Mass | 700.402039 |
| LogP | -0.33 |
| Index of Refraction | 1.619 |