Boc-Leu-Arg-Arg-AMC · 2 HCl

Modify Date: 2023-02-26 17:51:02

Boc-Leu-Arg-Arg-AMC · 2 HCl Structure
Boc-Leu-Arg-Arg-AMC · 2 HCl structure
Common Name Boc-Leu-Arg-Arg-AMC · 2 HCl
CAS Number 109358-46-5 Molecular Weight 700.829
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C33H52N10O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Boc-Leu-Arg-Arg-AMC · 2 HCl


Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core. Upon enzymatic cleavage by the 26S proteasome or 20S proteolytic core, amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify 26S proteasome or 20S proteolytic core trypsin-like activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.

 Names

Name Boc-Leu-Arg-Arg-AMC · 2 HCl
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C33H52N10O7
Molecular Weight 700.829
Exact Mass 700.402039
LogP -0.33
Index of Refraction 1.619

 Synonyms

L-Argininamide, N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-leucyl-L-arginyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide
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