201849-55-0

201849-55-0 structure

Name: Boc-Gln-Ala-Arg-AMC · HCl
Chemical Name: Boc-Gln-Ala-Arg-AMC · HCl
CAS Number: 201849-55-0
Molecular Formula: C₂₉H₄₃ClN₈O₈
Molecular Weight: 667.154
Catalog: Signaling Pathways Metabolic Enzyme/Protease Ser/Thr Protease
Create Date: 2018-03-21 08:38:06
Modify Date: 2024-01-10 13:06:40
Boc-Gln-Ala-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC hydrochloride can also be used for measuring the proteolytic activity of TMPRSS2[1][2].

Name	Boc-Gln-Ala-Arg-AMC · HCl
Synonyms	N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-glutaminyl-L-alanyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)-L-argininamide hydrochloride (1:1) L-Argininamide, N-[(1,1-dimethylethoxy)carbonyl]-L-glutaminyl-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, hydrochloride (1:1)

Description	Boc-Gln-Ala-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin. Boc-Gln-Ala-Arg-AMC hydrochloride can also be used for measuring the proteolytic activity of TMPRSS2[1][2].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Others
Target	Trypsin[1]
References	[1]. Mosztbacher D, et al. Measuring digestive protease activation in the mouse pancreas. Pancreatology. 2020 Mar;20(2):288-292. [2]. Ko CJ, et al. Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis. Oncogene. 2020 Sep;39(37):5950-5963.