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Boc-Gln-Arg-Arg-AMC

Names

[ CAS No. ]:
109376-05-8

[ Name ]:
Boc-Gln-Arg-Arg-AMC

[Synonym ]:
Boc-Gln-Arg-Arg-7-amido-4-methylcoumarin acetate salt
BOC-GLN-ARG-ARG-AMC ACOH
T-BUTYLOXYCARBONYL-L-GLUTAMINYL-L-ARGINYL-L-ARGININE 4-METHYLCOUMARYL-7-AMIDE
Boc-Gln-Arg-Arg-AMC
N-T-BOC-GLN-ARG-ARG 7-AMIDO-4-*METHYLCOUMARIN ACETAT
N-T-boc-gln-arg-arg 7-amido-4-*methylcoumarin ace
N-tert-BOC-Gln-Arg-Arg 7-amido-4-methylcoumarin acetate
BOC-GLN-ARG-ARG-MCA

Biological Activity

[Description]:

Boc-Gln-Arg-Arg-AMC is a fluorogenic substrate for the determination of protease activity. Boc-Gln-Arg-Arg-AMC undergoes hydrolysis and releases the fluorescent product 7-amino-4-methylcoumarin (AMC). AMC is fluorescent under UV light and can emit a fluorescent signal[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Tervonen TA, et, al. Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion. Oncogene. 2016 Apr 7;35(14):1832-46.  

Chemical & Physical Properties

[ Molecular Formula ]:
C32H49N11O8

[ Molecular Weight ]:
715.80

[ Exact Mass ]:
715.37700

[ PSA ]:
322.73000

[ LogP ]:
4.02270

Related Compounds