(D-Pro2,D-Trp6.8,Nle10)-Neurokinin B

Modify Date: 2024-01-27 13:10:29

(D-Pro2,D-Trp6.8,Nle10)-Neurokinin B structure	Common Name	(D-Pro2,D-Trp6.8,Nle10)-Neurokinin B
	CAS Number	109212-72-8	Molecular Weight	1326.50000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆₇H₈₇N₁₅O₁₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (D-Pro2,D-Trp6.8,Nle10)-Neurokinin B

(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B (Neurokinin Receptor) with a pA2 of 5.5. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B shows no influence on Substance P or Neurokinin A[1].

Name	[D-Pro2, D-Trp6,8, Nle10]-Neurokinin B,DpHDFwVwL-Nle-NH2
Synonym	More Synonyms

Description	(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B (Neurokinin Receptor) with a pA2 of 5.5. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B shows no influence on Substance P or Neurokinin A[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
In Vivo	在大鼠中，(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B (1 mg/kg i.v.) 显着减少 Substance P- 和 Neurokinin B-，但不减少乙酰胆碱或 Neurokinin A 诱导的流涎。(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B 可将麻醉大鼠的血压降低 35% 至 40%[2]。
References	[1]. H I Jacoby, et al. Differentiation of multiple neurokinin receptors in the guinea pig ileum. Life Sci. 1986 Nov 24;39(21):1995-2003. [2]. C W Murray, et al. Neurokinin-induced salivation in the anesthetized rat: a three receptor hypothesis. J Pharmacol Exp Ther. 1987 Aug;242(2):500-6.

Molecular Formula	C₆₇H₈₇N₁₅O₁₄
Molecular Weight	1326.50000
Exact Mass	1325.66000
PSA	457.08000
LogP	5.63230

ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2

(D-PRO2,D-TRP6,8,NLE10)-NEUROKININ B

(D-Pro2,D-Trp6

DPHDFWVWL-NLE-NH2

H-ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2

GL Biochem (Shanghai) Ltd.
China
Product Name: DpHDFwVwL-Nle-NH2
Price: $Inquiry/1kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: H-ASP-D-PRO-HIS-ASP-PHE-D-TRP-VAL-D-TRP-LEU-NLE-NH2
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: D-Pro2,D-Trp6,8,Nle10]-Neurokinin B
Price: $Inquiry/1kg
Purity: 99.0%
Stocking Period: 1 Day
Contact: Vinnie

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